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Adad1 adenosine deaminase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 21744, updated on 1-Mar-2024

Summary

Official Symbol
Adad1provided by MGI
Official Full Name
adenosine deaminase domain containing 1provided by MGI
Primary source
MGI:MGI:103258
See related
Ensembl:ENSMUSG00000027719 AllianceGenome:MGI:103258
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tenr
Summary
Enables RNA binding activity. Acts upstream of or within spermatid development. Located in nucleus. Is expressed in brain; genitourinary system; and inner ear. Orthologous to human ADAD1 (adenosine deaminase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 32.6) See more
Orthologs
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Genomic context

See Adad1 in Genome Data Viewer
Location:
3 B; 3 18.3 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (37117805..37165661)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (37063656..37111512)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase, mitochondrial 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_07428 Neighboring gene bridge-like lipid transfer protein family member 1 Neighboring gene STARR-seq mESC enhancer starr_07429 Neighboring gene STARR-seq mESC enhancer starr_07431 Neighboring gene STARR-seq mESC enhancer starr_07432 Neighboring gene zinc finger, CCHC domain containing 17 pseudogene Neighboring gene nucleophosmin 1 pseudogene Neighboring gene predicted gene 12584 Neighboring gene interleukin 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables adenosine deaminase activity IEA
Inferred from Electronic Annotation
more info
 
enables double-stranded RNA adenosine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tRNA-specific adenosine deaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in RNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in adenosine to inosine editing IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
NOT acts_upstream_of_or_within regulation of translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spermatid development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatid development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in male germ cell nucleus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
adenosine deaminase domain-containing protein 1
Names
adenosine deaminase domain containing 1 (testis specific)
testis nuclear RNA binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009350.3NP_033376.2  adenosine deaminase domain-containing protein 1

    See identical proteins and their annotated locations for NP_033376.2

    Status: VALIDATED

    Source sequence(s)
    AL662823
    Consensus CDS
    CCDS17315.1
    UniProtKB/Swiss-Prot
    A2AAD7, A2AAD8, A2AAV1, Q08EL2, Q3V0N7, Q5SUE7, Q62309, Q9JLB6
    UniProtKB/TrEMBL
    F8WI80
    Related
    ENSMUSP00000115260.2, ENSMUST00000144629.8
    Conserved Domains (2) summary
    smart00358
    Location:139204
    DSRM; Double-stranded RNA binding motif
    smart00552
    Location:246618
    ADEAMc; tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    37117805..37165661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)