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Nol10 nucleolar protein 10 [ Mus musculus (house mouse) ]

Gene ID: 217431, updated on 26-Sep-2022

Summary

Official Symbol
Nol10provided by MGI
Official Full Name
nucleolar protein 10provided by MGI
Primary source
MGI:MGI:2684913
See related
Ensembl:ENSMUSG00000061458 AllianceGenome:MGI:2684913
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm67
Summary
Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleus. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human NOL10 (nucleolar protein 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 8.6), CNS E14 (RPKM 5.4) and 27 other tissues See more
Orthologs
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Genomic context

See Nol10 in Genome Data Viewer
Location:
12; 12 A1.1
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (17398423..17480101)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (17348421..17430095)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene protein disulfide isomerase associated 6 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit C2 Neighboring gene predicted gene, 46336 Neighboring gene microRNA 3066 Neighboring gene predicted gene, 36752 Neighboring gene predicted gene, 46325

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC113734

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008421.1NP_001008421.1  nucleolar protein 10

    See identical proteins and their annotated locations for NP_001008421.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086676
    Consensus CDS
    CCDS25828.1
    UniProtKB/Swiss-Prot
    Q5RJG1
    UniProtKB/TrEMBL
    Q3TUB5
    Related
    ENSMUSP00000035930.11, ENSMUST00000046011.12
    Conserved Domains (4) summary
    COG2319
    Location:56312
    WD40; WD40 repeat [General function prediction only]
    pfam08159
    Location:482508
    NUC153; NUC153 domain
    sd00039
    Location:5595
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:182339
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    17398423..17480101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017315015.3XP_017170504.1  nucleolar protein 10 isoform X1

    Conserved Domains (4) summary
    COG4942
    Location:507632
    EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
    sd00039
    Location:545
    7WD40; WD40 repeat [structural motif]
    pfam08159
    Location:432458
    NUC153; NUC153 domain
    cl29593
    Location:132289
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...