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Heatr6 HEAT repeat containing 6 [ Mus musculus (house mouse) ]

Gene ID: 217026, updated on 26-Sep-2022

Summary

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Official Symbol
Heatr6provided by MGI
Official Full Name
HEAT repeat containing 6provided by MGI
Primary source
MGI:MGI:1919790
See related
Ensembl:ENSMUSG00000000976 AllianceGenome:MGI:1919790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2700008B19Rik
Summary
Orthologous to human HEATR6 (HEAT repeat containing 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 7.8), whole brain E14.5 (RPKM 7.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Heatr6 in Genome Data Viewer
Location:
11; 11 C
Exon count:
20
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (83644463..83674580)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83753637..83783754)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 18 Neighboring gene WAP four-disulfide core domain 21 Neighboring gene COMM domain containing 9 pseudogene Neighboring gene predicted gene, 38934

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery. Baines K, et al. Autophagy Rep, 2022. PMID 35449600, Free PMC Article
  2. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  5. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ22087

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
HEAT repeat-containing protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145432.3 → NP_663407.2  HEAT repeat-containing protein 6

    See identical proteins and their annotated locations for NP_663407.2

    Status: VALIDATED

    Source sequence(s)
    AA183118, AK132494, AK138219, BC065092, DV657360
    Consensus CDS
    CCDS36259.1
    UniProtKB/Swiss-Prot
    Q6P1G0, Q9CSQ4
    Related
    ENSMUSP00000001002.8, ENSMUST00000001002.8
    Conserved Domains (2) summary
    pfam13251
    Location:421 → 602
    DUF4042; Domain of unknown function (DUF4042)
    sd00044
    Location:817 → 846
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    83644463..83674580
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017314468.2 → XP_017169957.1  HEAT repeat-containing protein 6 isoform X2

    Conserved Domains (2) summary
    sd00044
    Location:353 → 382
    HEAT; HEAT repeat [structural motif]
    pfam13251
    Location:1 → 138
    DUF4042; Domain of unknown function (DUF4042)

  2. XM_030245843.1 → XP_030101703.1  HEAT repeat-containing protein 6 isoform X1

    Conserved Domains (2) summary
    sd00044
    Location:467 → 496
    HEAT; HEAT repeat [structural motif]
    pfam13251
    Location:71 → 252
    DUF4042; Domain of unknown function (DUF4042)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P1G0.1 GenPept UniProtKB/Swiss-Prot:Q6P1G0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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