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Mfap3 microfibrillar-associated protein 3 [ Mus musculus (house mouse) ]

Gene ID: 216760, updated on 12-May-2024

Summary

Official Symbol
Mfap3provided by MGI
Official Full Name
microfibrillar-associated protein 3provided by MGI
Primary source
MGI:MGI:1924068
See related
Ensembl:ENSMUSG00000020522 AllianceGenome:MGI:1924068
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610509F16Rik; 2700079M14Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Is expressed in genitourinary system and heart ventricle. Orthologous to human MFAP3 (microfibril associated protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 10.8), CNS E14 (RPKM 10.2) and 28 other tissues See more
Orthologs
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Genomic context

See Mfap3 in Genome Data Viewer
Location:
11 B1.3; 11 35.27 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (57409478..57424643)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (57518652..57533817)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S6 pseudogene Neighboring gene predicted gene, 53706 Neighboring gene family with sequence similarity 114, member A2 Neighboring gene STARR-positive B cell enhancer ABC_E1825 Neighboring gene STARR-seq mESC enhancer starr_29572 Neighboring gene predicted gene, 51895 Neighboring gene RIKEN cDNA 4933424L21 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:57458544-57458653 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 10

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
microfibril-associated glycoprotein 3
Names
novel immunoglobulin domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145426.2NP_663401.2  microfibril-associated glycoprotein 3 precursor

    See identical proteins and their annotated locations for NP_663401.2

    Status: VALIDATED

    Source sequence(s)
    AK042988, AL672236, BY203406, CF174749
    Consensus CDS
    CCDS24718.1
    UniProtKB/Swiss-Prot
    Q8BHK5, Q922T2
    UniProtKB/TrEMBL
    A0A0R4J1C7
    Related
    ENSMUSP00000020830.8, ENSMUST00000020830.14
    Conserved Domains (1) summary
    smart00408
    Location:60123
    IGc2; Immunoglobulin C-2 Type
  2. NM_180599.1NP_850930.1  microfibril-associated glycoprotein 3 precursor

    See identical proteins and their annotated locations for NP_850930.1

    Status: VALIDATED

    Source sequence(s)
    AL672236, CF174749
    Consensus CDS
    CCDS24718.1
    UniProtKB/Swiss-Prot
    Q8BHK5, Q922T2
    UniProtKB/TrEMBL
    A0A0R4J1C7
    Related
    ENSMUSP00000104477.2, ENSMUST00000108849.8
    Conserved Domains (1) summary
    smart00408
    Location:60123
    IGc2; Immunoglobulin C-2 Type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    57409478..57424643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532851.1XP_006532914.1  microfibril-associated glycoprotein 3 isoform X2

  2. XM_006532850.4XP_006532913.1  microfibril-associated glycoprotein 3 isoform X1

    See identical proteins and their annotated locations for XP_006532913.1

    UniProtKB/Swiss-Prot
    Q8BHK5, Q922T2
    UniProtKB/TrEMBL
    A0A0R4J1C7
    Conserved Domains (1) summary
    smart00408
    Location:60123
    IGc2; Immunoglobulin C-2 Type