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Zfc3h1 zinc finger, C3H1-type containing [ Mus musculus (house mouse) ]

Gene ID: 216345, updated on 30-Apr-2024

Summary

Official Symbol
Zfc3h1provided by MGI
Official Full Name
zinc finger, C3H1-type containingprovided by MGI
Primary source
MGI:MGI:2446143
See related
Ensembl:ENSMUSG00000034163 AllianceGenome:MGI:2446143
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Psrc2; Ccdc131
Summary
Predicted to be part of exosome (RNase complex). Predicted to be active in nucleus. Orthologous to human ZFC3H1 (zinc finger C3H1-type containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 11.2), CNS E14 (RPKM 10.6) and 28 other tissues See more
Orthologs
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Genomic context

See Zfc3h1 in Genome Data Viewer
Location:
10 D2; 10 63.51 cM
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (115220691..115268677)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (115384799..115432772)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_27939 Neighboring gene STARR-seq mESC enhancer starr_27942 Neighboring gene transmembrane protein 19 Neighboring gene soc-2 (suppressor of clear) homolog pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1128 Neighboring gene THAP domain containing, apoptosis associated protein 2 Neighboring gene predicted gene, 53633 Neighboring gene leucine rich repeat containing G protein coupled receptor 5 Neighboring gene STARR-positive B cell enhancer mm9_chr10:114916114-114916415 Neighboring gene STARR-seq mESC enhancer starr_27944 Neighboring gene RIKEN cDNA A930009A15 gene Neighboring gene ribosomal protein S3A pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of exosome (RNase complex) IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of exosome (RNase complex) ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger C3H1 domain-containing protein
Names
coiled-coil domain containing 131
proline/serine-rich coiled-coil 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033261.2NP_001028433.2  zinc finger C3H1 domain-containing protein

    See identical proteins and their annotated locations for NP_001028433.2

    Status: VALIDATED

    Source sequence(s)
    AK145652, AK172969
    Consensus CDS
    CCDS36062.1
    UniProtKB/TrEMBL
    B2RT41, Q6A049
    Related
    ENSMUSP00000044069.9, ENSMUST00000036044.9
    Conserved Domains (3) summary
    sd00006
    Location:16071633
    TPR; TPR repeat [structural motif]
    pfam10650
    Location:11891207
    zf-C3H1; Putative zinc-finger domain
    pfam13414
    Location:16071670
    TPR_11; TPR repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    115220691..115268677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513538.5XP_006513601.1  zinc finger C3H1 domain-containing protein isoform X1

    UniProtKB/TrEMBL
    Q6A049
    Conserved Domains (5) summary
    TIGR02168
    Location:7381010
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02917
    Location:13541682
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:16081634
    TPR; TPR repeat [structural motif]
    pfam02463
    Location:201998
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam10650
    Location:11891209
    zf-C3H1; Putative zinc-finger domain
  2. XM_006513540.5XP_006513603.1  zinc finger C3H1 domain-containing protein isoform X3

    UniProtKB/TrEMBL
    Q6A049
    Conserved Domains (5) summary
    TIGR02168
    Location:7381010
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02917
    Location:13541682
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:16081634
    TPR; TPR repeat [structural motif]
    pfam02463
    Location:201998
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam10650
    Location:11891209
    zf-C3H1; Putative zinc-finger domain
  3. XM_006513539.5XP_006513602.1  zinc finger C3H1 domain-containing protein isoform X2

    UniProtKB/TrEMBL
    Q6A049
    Conserved Domains (5) summary
    TIGR02168
    Location:7371009
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02917
    Location:13531681
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:16071633
    TPR; TPR repeat [structural motif]
    pfam02463
    Location:201997
    SMC_N; RecF/RecN/SMC N terminal domain
    pfam10650
    Location:11881208
    zf-C3H1; Putative zinc-finger domain
  4. XM_017313907.3XP_017169396.1  zinc finger C3H1 domain-containing protein isoform X5

    UniProtKB/TrEMBL
    Q6P7T8
    Conserved Domains (3) summary
    TIGR02917
    Location:408736
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:662688
    TPR; TPR repeat [structural motif]
    pfam10650
    Location:243263
    zf-C3H1; Putative zinc-finger domain
  5. XM_036155758.1XP_036011651.1  zinc finger C3H1 domain-containing protein isoform X4

    UniProtKB/TrEMBL
    Q6P7T8
    Conserved Domains (3) summary
    TIGR02917
    Location:408736
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:662688
    TPR; TPR repeat [structural motif]
    pfam10650
    Location:243262
    zf-C3H1; Putative zinc-finger domain

RNA

  1. XR_003948675.2 RNA Sequence

  2. XR_003948676.2 RNA Sequence