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Tmem259 transmembrane protein 259 [ Mus musculus (house mouse) ]

Gene ID: 216157, updated on 23-Jun-2021

Summary

Official Symbol
Tmem259provided by MGI
Official Full Name
transmembrane protein 259provided by MGI
Primary source
MGI:MGI:2177957
See related
Ensembl:ENSMUSG00000013858
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
memb; ORF61; R32184_3; mFLJ00277; AC087114.7gm2
Expression
Ubiquitous expression in adrenal adult (RPKM 266.2), duodenum adult (RPKM 252.2) and 28 other tissues See more
Orthologs
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Genomic context

See Tmem259 in Genome Data Viewer
Location:
10; 10 C1
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (79812954..79820159, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (79977120..79984325, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (79439865..79447075, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene AT rich interactive domain 3A (BRIGHT-like) Neighboring gene WD repeat domain 18 Neighboring gene glutamate receptor, ionotropic, NMDA3B Neighboring gene predicted gene, 26243 Neighboring gene calponin 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ00277, MGC90890, AC087114.7gm12

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003949.4NP_001003949.2  membralin isoform 2

    See identical proteins and their annotated locations for NP_001003949.2

    Status: VALIDATED

    Source sequence(s)
    AC151846, BE947335, BQ571954, BQ572278, CO044817, CX205815
    Consensus CDS
    CCDS24002.1
    UniProtKB/Swiss-Prot
    Q8CIV2
    Related
    ENSMUSP00000056792.8, ENSMUST00000052885.14
    Conserved Domains (1) summary
    pfam09746
    Location:34393
    Membralin; Tumour-associated protein
  2. NM_001359632.1NP_001346561.1  membralin isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC151846, BE947335, BQ571954, BQ572278, BQ748980, CO044817, CX205815
    Related
    ENSMUSP00000119572.2, ENSMUST00000124536.2
    Conserved Domains (2) summary
    pfam09746
    Location:35417
    Membralin; tumor-associated protein
    cl28033
    Location:484596
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    79812954..79820159 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513491.1XP_006513554.1  membralin isoform X1

    See identical proteins and their annotated locations for XP_006513554.1

    Conserved Domains (2) summary
    PHA03307
    Location:443555
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam09746
    Location:34376
    Membralin; tumor-associated protein
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