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Ybey ybeY metallopeptidase [ Mus musculus (house mouse) ]

Gene ID: 216119, updated on 5-Jan-2023


Official Symbol
Ybeyprovided by MGI
Official Full Name
ybeY metallopeptidaseprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000033126 AllianceGenome:MGI:2656825
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ORF57; ORF66; C21orf57; 1110068N23Rik; A130042E20Rik
Predicted to enable endoribonuclease activity. Predicted to be involved in rRNA processing. Located in mitochondrion. Is expressed in several structures, including genitourinary system; liver; nervous system; sensory organ; and surface ectoderm. Orthologous to human YBEY (ybeY metalloendoribonuclease). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in ovary adult (RPKM 2.8), lung adult (RPKM 2.4) and 28 other tissues See more
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Genomic context

See Ybey in Genome Data Viewer
10; 10 C1
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (76295401..76304948, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (76457252..76469114, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene disco interacting protein 2 homolog A Neighboring gene predicted gene, 40699 Neighboring gene RIKEN cDNA 1700094J05 gene Neighboring gene pericentrin (kendrin) Neighboring gene RIKEN cDNA 2610028H24 gene Neighboring gene minichromosome maintenance complex component 3 associated protein Neighboring gene RIKEN cDNA 4930483K19 gene Neighboring gene lanosterol synthase Neighboring gene spermatogenesis and centriole associated 1 like Neighboring gene predicted gene 15343

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

General gene information



Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA endonuclease activity ISO
Inferred from Sequence Orthology
more info
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
Process Evidence Code Pubs
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
endoribonuclease YbeY
putative metalloprotease C21orf57 homolog
putative ribonuclease
rRNA maturation factor homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172550.4NP_766138.3  endoribonuclease YbeY

    See identical proteins and their annotated locations for NP_766138.3

    Status: VALIDATED

    Source sequence(s)
    AK136543, BC057308
    Consensus CDS
    Q6PG17, Q8CAV0
    ENSMUSP00000045647.5, ENSMUST00000049185.6
    Conserved Domains (1) summary
    TIGR00043; rRNA maturation RNase YbeY

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000076.7 Reference GRCm39 C57BL/6J

    76295401..76304948 complement
    GenBank, FASTA, Sequence Viewer (Graphics)