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Lrrc20 leucine rich repeat containing 20 [ Mus musculus (house mouse) ]

Gene ID: 216011, updated on 8-May-2024

Summary

Official Symbol
Lrrc20provided by MGI
Official Full Name
leucine rich repeat containing 20provided by MGI
Primary source
MGI:MGI:2387182
See related
Ensembl:ENSMUSG00000037151 AllianceGenome:MGI:2387182
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Is expressed in embryo and forelimb bud. Orthologous to human LRRC20 (leucine rich repeat containing 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 15.7), mammary gland adult (RPKM 10.5) and 28 other tissues See more
Orthologs
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Genomic context

See Lrrc20 in Genome Data Viewer
Location:
10 B4; 10 32.22 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (61311579..61418570)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (61475769..61582791)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene nodal growth differentiation factor Neighboring gene eukaryotic translation initiation factor 4E binding protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E3888 Neighboring gene STARR-seq mESC enhancer starr_26847 Neighboring gene RIKEN cDNA D830039M14 gene Neighboring gene STARR-positive B cell enhancer ABC_E6860 Neighboring gene predicted gene, 47593 Neighboring gene oligosaccharyltransferase complex subunit pseudogene Neighboring gene STARR-seq mESC enhancer starr_26850 Neighboring gene predicted gene 28447 Neighboring gene neuropeptide FF receptor 1 Neighboring gene STARR-positive B cell enhancer ABC_E10613 Neighboring gene STARR-positive B cell enhancer ABC_E6861 Neighboring gene pyrophosphatase (inorganic) 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (3)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC25719

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
leucine-rich repeat-containing protein 20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153542.1NP_705770.1  leucine-rich repeat-containing protein 20

    See identical proteins and their annotated locations for NP_705770.1

    Status: PROVISIONAL

    Source sequence(s)
    BC036304
    Consensus CDS
    CCDS23881.1
    UniProtKB/Swiss-Prot
    Q8CI70
    Related
    ENSMUSP00000048042.8, ENSMUST00000049242.9
    Conserved Domains (4) summary
    cd00116
    Location:22158
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00031
    Location:7698
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:2651
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:98156
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    61311579..61418570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017313885.1XP_017169374.1  leucine-rich repeat-containing protein 20 isoform X2

  2. XM_017313884.1XP_017169373.1  leucine-rich repeat-containing protein 20 isoform X1

    Conserved Domains (2) summary
    PLN03150
    Location:39110
    PLN03150; hypothetical protein; Provisional
    sd00031
    Location:2848
    LRR_1; leucine-rich repeat [structural motif]
  3. XM_006513472.5XP_006513535.1  leucine-rich repeat-containing protein 20 isoform X3

    Conserved Domains (2) summary
    PLN03150
    Location:2091
    PLN03150; hypothetical protein; Provisional
    sd00031
    Location:729
    LRR_1; leucine-rich repeat [structural motif]