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Adgb androglobin [ Mus musculus (house mouse) ]

Gene ID: 215772, updated on 5-Mar-2024

Summary

Official Symbol
Adgbprovided by MGI
Official Full Name
androglobinprovided by MGI
Primary source
MGI:MGI:3605549
See related
Ensembl:ENSMUSG00000050994 AllianceGenome:MGI:3605549
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9130014G24Rik
Summary
Predicted to enable calcium-dependent cysteine-type endopeptidase activity; heme binding activity; and oxygen binding activity. Predicted to be involved in proteolysis. Is expressed in lung. Orthologous to human ADGB (androglobin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 5.3), liver E18 (RPKM 0.6) and 3 other tissues See more
Orthologs
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Genomic context

See Adgb in Genome Data Viewer
Location:
10 A1; 10 3.44 cM
Exon count:
39
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (10211447..10350837, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (10335703..10475093, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930598N05 gene Neighboring gene predicted gene, 31904 Neighboring gene STARR-seq mESC enhancer starr_25741 Neighboring gene STARR-positive B cell enhancer mm9_chr10:10055172-10055473 Neighboring gene eukaryotic translation initiation factor 4A1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_25742 Neighboring gene STARR-seq mESC enhancer starr_25744 Neighboring gene STARR-seq mESC enhancer starr_25746 Neighboring gene RAB32, member RAS oncogene family Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables oxygen binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
involved_in spermatid development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IEA
Inferred from Electronic Annotation
more info
 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 
located_in sperm annulus IDA
Inferred from Direct Assay
more info
PubMed 
located_in sperm flagellum IDA
Inferred from Direct Assay
more info
PubMed 
located_in sperm midpiece IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
androglobin
Names
calpain-7-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127353.4NP_001120825.3  androglobin

    Status: VALIDATED

    Source sequence(s)
    AC153567, AC159380
    UniProtKB/TrEMBL
    J3QMP3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    10211447..10350837 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243163.3XP_011241465.1  androglobin isoform X5

    UniProtKB/TrEMBL
    A0A140LI36
    Conserved Domains (2) summary
    PTZ00121
    Location:12841651
    PTZ00121; MAEBL; Provisional
    cl00051
    Location:200307
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
  2. XM_017313876.2XP_017169365.1  androglobin isoform X4

    UniProtKB/Swiss-Prot
    G3UZ78, Q8C5C7
    Conserved Domains (2) summary
    PTZ00121
    Location:13101677
    PTZ00121; MAEBL; Provisional
    cl00051
    Location:200307
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
  3. XM_030244999.1XP_030100859.1  androglobin isoform X7

    UniProtKB/Swiss-Prot
    G3UZ78, Q8C5C7
    Conserved Domains (2) summary
    pfam09731
    Location:13291639
    Mitofilin; Mitochondrial inner membrane protein
    cl00051
    Location:200307
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
  4. XM_011243160.3XP_011241462.1  androglobin isoform X2

    UniProtKB/Swiss-Prot
    G3UZ78, Q8C5C7
    Conserved Domains (2) summary
    PTZ00121
    Location:13281695
    PTZ00121; MAEBL; Provisional
    cl00051
    Location:200307
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
  5. XM_017313877.2XP_017169366.1  androglobin isoform X6

    UniProtKB/Swiss-Prot
    G3UZ78, Q8C5C7
    Conserved Domains (2) summary
    PTZ00121
    Location:13321640
    PTZ00121; MAEBL; Provisional
    cl00051
    Location:200307
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
  6. XM_017313875.2XP_017169364.1  androglobin isoform X1

    UniProtKB/Swiss-Prot
    G3UZ78, Q8C5C7
    Conserved Domains (2) summary
    PTZ00121
    Location:13291696
    PTZ00121; MAEBL; Provisional
    cl00051
    Location:200307
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
  7. XM_017313879.3XP_017169368.1  androglobin isoform X10

    UniProtKB/Swiss-Prot
    G3UZ78, Q8C5C7
    Related
    ENSMUSP00000134378.2, ENSMUST00000172530.8
    Conserved Domains (2) summary
    PTZ00121
    Location:12961663
    PTZ00121; MAEBL; Provisional
    cl00051
    Location:186293
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
  8. XM_006512658.5XP_006512721.1  androglobin isoform X3

    UniProtKB/Swiss-Prot
    G3UZ78, Q8C5C7
    Conserved Domains (2) summary
    PTZ00121
    Location:13151682
    PTZ00121; MAEBL; Provisional
    cl00051
    Location:186293
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
  9. XM_006512663.4XP_006512726.1  androglobin isoform X8

    Conserved Domains (1) summary
    PTZ00121
    Location:8961263
    PTZ00121; MAEBL; Provisional
  10. XM_017313878.2XP_017169367.1  androglobin isoform X9

    Conserved Domains (1) summary
    cl00051
    Location:200307
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_172547.3: Suppressed sequence

    Description
    NM_172547.3: This RefSeq was temporarily suppressed because the CDS was partial.