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Kri1 KRI1 homolog [ Mus musculus (house mouse) ]

Gene ID: 215194, updated on 30-Apr-2024

Summary

Official Symbol
Kri1provided by MGI
Official Full Name
KRI1 homologprovided by MGI
Primary source
MGI:MGI:2384899
See related
Ensembl:ENSMUSG00000035047 AllianceGenome:MGI:2384899
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of 90S preribosome. Predicted to be active in nucleolus. Is expressed in cervico-thoracic ganglion; tail dorsal root ganglion; and thymus primordium. Orthologous to human KRI1 (KRI1 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 14.5), thymus adult (RPKM 12.2) and 28 other tissues See more
Orthologs
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Genomic context

See Kri1 in Genome Data Viewer
Location:
9 A3; 9 7.76 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21184753..21199265, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21273457..21287969, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 16754 Neighboring gene STARR-seq mESC enhancer starr_23486 Neighboring gene kelch-like ECH-associated protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E8278 Neighboring gene sphingosine-1-phosphate receptor 5 Neighboring gene STARR-positive B cell enhancer mm9_chr9:21069491-21069792 Neighboring gene autophagy related 4D, cysteine peptidase Neighboring gene cyclin dependent kinase inhibitor 2D Neighboring gene adaptor protein complex AP-1, mu 2 subunit

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145416.3NP_663391.2  protein KRI1 homolog

    See identical proteins and their annotated locations for NP_663391.2

    Status: VALIDATED

    Source sequence(s)
    BI989088, BQ557175, CJ069606, CK795617, CO426049, CO426749, CX562209
    Consensus CDS
    CCDS72201.1
    UniProtKB/Swiss-Prot
    Q8VDQ9
    UniProtKB/TrEMBL
    F6WIU1
    Related
    ENSMUSP00000039688.4, ENSMUST00000038671.10
    Conserved Domains (2) summary
    pfam05178
    Location:340410
    Kri1; KRI1-like family
    pfam12936
    Location:501589
    Kri1_C; KRI1-like family C-terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    21184753..21199265 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)