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Slc43a2 solute carrier family 43, member 2 [ Mus musculus (house mouse) ]

Gene ID: 215113, updated on 12-May-2024

Summary

Official Symbol
Slc43a2provided by MGI
Official Full Name
solute carrier family 43, member 2provided by MGI
Primary source
MGI:MGI:2442746
See related
Ensembl:ENSMUSG00000038178 AllianceGenome:MGI:2442746
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lat4; 7630402D21Rik
Summary
Enables L-amino acid transmembrane transporter activity. Acts upstream of or within L-amino acid transport. Located in plasma membrane. Is expressed in several structures, including adrenal medulla; metanephros; nephric duct of male; nervous system; and sensory organ. Orthologous to human SLC43A2 (solute carrier family 43 member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in duodenum adult (RPKM 79.3), small intestine adult (RPKM 65.9) and 19 other tissues See more
Orthologs
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Genomic context

See Slc43a2 in Genome Data Viewer
Location:
11 B5; 11 45.92 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (75420741..75468401)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (75529915..75577575)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7017 Neighboring gene scavenger receptor class F, member 1 Neighboring gene Rab interacting lysosomal protein Neighboring gene STARR-positive B cell enhancer ABC_E9036 Neighboring gene STARR-positive B cell enhancer ABC_E10689 Neighboring gene STARR-seq mESC enhancer starr_29997 Neighboring gene predicted gene 45606 Neighboring gene microRNA 3971 Neighboring gene STARR-positive B cell enhancer ABC_E10690 Neighboring gene STARR-positive B cell enhancer ABC_E9366 Neighboring gene STARR-positive B cell enhancer ABC_E9827 Neighboring gene STARR-positive B cell enhancer ABC_E9367 Neighboring gene RIKEN cDNA 4931413K12 gene Neighboring gene predicted gene, 53686 Neighboring gene phosphatidylinositol transfer protein, alpha Neighboring gene cytochrome c oxidase, subunit VIIc pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC28931

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
large neutral amino acids transporter small subunit 4
Names
L-type amino L-acid transporter 4
L-type amino acid transporter 4

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199283.1NP_001186212.1  large neutral amino acids transporter small subunit 4

    See identical proteins and their annotated locations for NP_001186212.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
    Source sequence(s)
    AA017978, AK143773, AL591440, AL591496
    Consensus CDS
    CCDS25051.1
    UniProtKB/Swiss-Prot
    Q5CD76, Q8CGA3
    Related
    ENSMUSP00000126838.3, ENSMUST00000169547.9
    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  2. NM_001199284.1NP_001186213.1  large neutral amino acids transporter small subunit 4

    See identical proteins and their annotated locations for NP_001186213.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains a different segment from its 5' UTR, compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AA017978, AB120363, AK143773, AL591440, BY202700
    Consensus CDS
    CCDS25051.1
    UniProtKB/Swiss-Prot
    Q5CD76, Q8CGA3
    Related
    ENSMUSP00000104071.2, ENSMUST00000108433.8
    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  3. NM_173388.2NP_775564.1  large neutral amino acids transporter small subunit 4

    See identical proteins and their annotated locations for NP_775564.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains a different segment from its 5' UTR, compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AA017978, AK143773, AL591440, BY202700, CD550550
    Consensus CDS
    CCDS25051.1
    UniProtKB/Swiss-Prot
    Q5CD76, Q8CGA3
    Related
    ENSMUSP00000046074.8, ENSMUST00000042561.14
    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    75420741..75468401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532825.4XP_006532888.1  large neutral amino acids transporter small subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006532888.1

    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  2. XM_030245780.2XP_030101640.1  large neutral amino acids transporter small subunit 4 isoform X2

    UniProtKB/Swiss-Prot
    Q5CD76, Q8CGA3
    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  3. XM_006532819.4XP_006532882.1  large neutral amino acids transporter small subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006532882.1

    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  4. XM_006532827.5XP_006532890.1  large neutral amino acids transporter small subunit 4 isoform X2

    See identical proteins and their annotated locations for XP_006532890.1

    UniProtKB/Swiss-Prot
    Q5CD76, Q8CGA3
    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  5. XM_036156511.1XP_036012404.1  large neutral amino acids transporter small subunit 4 isoform X2

    UniProtKB/Swiss-Prot
    Q5CD76, Q8CGA3
    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  6. XM_006532826.5XP_006532889.1  large neutral amino acids transporter small subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006532889.1

    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  7. XM_006532820.4XP_006532883.1  large neutral amino acids transporter small subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006532883.1

    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  8. XM_006532823.4XP_006532886.1  large neutral amino acids transporter small subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006532886.1

    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  9. XM_006532821.4XP_006532884.1  large neutral amino acids transporter small subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006532884.1

    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  10. XM_006532824.4XP_006532887.1  large neutral amino acids transporter small subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006532887.1

    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  11. XM_006532822.5XP_006532885.1  large neutral amino acids transporter small subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006532885.1

    Conserved Domains (1) summary
    cd06174
    Location:90239
    MFS; Major Facilitator Superfamily
  12. XM_036156512.1XP_036012405.1  large neutral amino acids transporter small subunit 4 isoform X3

RNA

  1. XR_003949380.2 RNA Sequence