Format

Send to:

Choose Destination

Tcf15 transcription factor 15 [ Mus musculus (house mouse) ]

Gene ID: 21407, updated on 16-Oct-2021

Summary

Official Symbol
Tcf15provided by MGI
Official Full Name
transcription factor 15provided by MGI
Primary source
MGI:MGI:104664
See related
Ensembl:ENSMUSG00000068079
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Meso1; bHLH-EC2
Expression
Broad expression in adrenal adult (RPKM 9.0), mammary gland adult (RPKM 8.9) and 18 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tcf15 in Genome Data Viewer
Location:
2 G3; 2 74.83 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (151984973..151991017)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (152143056..152149097)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (151969345..151974833)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene sulfiredoxin 1 homolog (S. cerevisiae) Neighboring gene predicted gene, 31535 Neighboring gene ribosomal protein S15A, pseudogene 7 Neighboring gene casein kinase 2, alpha 1 polypeptide

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within anterior/posterior pattern specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in developmental process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within ear development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within eating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within establishment of epithelial cell apical/basal polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within mesenchymal to epithelial transition IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within muscle organ development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within muscle organ morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of hematopoietic stem cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within neuromuscular process controlling posture IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within paraxial mesoderm development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of stem cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within post-anal tail morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of extracellular matrix organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within respiratory system process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within skeletal system morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within skin development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within somitogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in stem cell population maintenance IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
transcription factor 15
Names
TCF-15
paraxis
protein bHLH-EC2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009328.2NP_033354.2  transcription factor 15

    See identical proteins and their annotated locations for NP_033354.2

    Status: PROVISIONAL

    Source sequence(s)
    BC027533
    Consensus CDS
    CCDS16878.1
    UniProtKB/Swiss-Prot
    Q60756
    Related
    ENSMUSP00000086511.6, ENSMUST00000089112.6
    Conserved Domains (1) summary
    pfam00010
    Location:71122
    HLH; Helix-loop-helix DNA-binding domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    151984973..151991017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499100.5XP_006499163.1  transcription factor 15 isoform X1

    Conserved Domains (1) summary
    cd11470
    Location:131196
    bHLH_TS_TCF15_paraxis; basic helix-loop-helix (bHLH) domain found in transcription factor 15 (TCF-15) and similar proteins
Support Center