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Fbxl21 F-box and leucine-rich repeat protein 21 [ Mus musculus (house mouse) ]

Gene ID: 213311, updated on 24-Oct-2019

Summary

Official Symbol
Fbxl21provided by MGI
Official Full Name
F-box and leucine-rich repeat protein 21provided by MGI
Primary source
MGI:MGI:2442921
See related
Ensembl:ENSMUSG00000035509
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FBL3B; Psttm; FBXL3B; D630045D17Rik
Expression
Low expression observed in reference dataset See more

Genomic context

See Fbxl21 in Genome Data Viewer
Location:
13; 13 B1
Exon count:
9
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (56522388..56537898)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (56623869..56639147)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 25, member 48 Neighboring gene interleukin 9 Neighboring gene leukocyte cell-derived chemotaxin 2 Neighboring gene RIKEN cDNA 2010203P06 gene Neighboring gene predicted gene, 32759

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Chemically induced (ENU) (1) 

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
contributes_to ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
G2/M transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
entrainment of circadian clock by photoperiod IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
entrainment of circadian clock by photoperiod IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein ubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
regulation of cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
rhythmic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
SCF ubiquitin ligase complex IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
F-box/LRR-repeat protein 21
Names
F-box and leucine-rich repeat protein 3B
F-box/LRR-repeat protein 3B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001346732.1NP_001333661.1  F-box/LRR-repeat protein 21 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC132901, AK035290, AK079800
    Consensus CDS
    CCDS84026.1
    UniProtKB/Swiss-Prot
    Q8BFZ4
    UniProtKB/TrEMBL
    G3X9Y3
    Related
    ENSMUSP00000112518.1, ENSMUST00000121871.7
  2. NM_001359807.1NP_001346736.1  F-box/LRR-repeat protein 21 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK079800, BE946365
    Consensus CDS
    CCDS88461.1
    Related
    ENSMUSP00000112714.1, ENSMUST00000121095.7
    Conserved Domains (1) summary
    pfam12937
    Location:68111
    F-box-like; F-box-like
  3. NM_178674.5NP_848789.2  F-box/LRR-repeat protein 21 isoform 1

    See identical proteins and their annotated locations for NP_848789.2

    Status: VALIDATED

    Source sequence(s)
    AK035290, AK079800, AK085598
    Consensus CDS
    CCDS26563.1
    UniProtKB/Swiss-Prot
    Q8BFZ4
    Related
    ENSMUSP00000035248.6, ENSMUST00000045428.6
    Conserved Domains (3) summary
    cd09293
    Location:333398
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:180205
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:4285
    F-box-like; F-box-like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p6 C57BL/6J

    Range
    56522388..56537898
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017315478.2XP_017170967.1  F-box/LRR-repeat protein 21 isoform X2

    Conserved Domains (1) summary
    pfam12937
    Location:68111
    F-box-like; F-box-like
  2. XM_011244507.3XP_011242809.1  F-box/LRR-repeat protein 21 isoform X2

    Conserved Domains (1) summary
    pfam12937
    Location:68111
    F-box-like; F-box-like
  3. XM_011244506.3XP_011242808.1  F-box/LRR-repeat protein 21 isoform X1

    Conserved Domains (1) summary
    pfam12937
    Location:68111
    F-box-like; F-box-like
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