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Itga10 integrin, alpha 10 [ Mus musculus (house mouse) ]

Gene ID: 213119, updated on 26-Jun-2020

Summary

Official Symbol
Itga10provided by MGI
Official Full Name
integrin, alpha 10provided by MGI
Primary source
MGI:MGI:2153482
See related
Ensembl:ENSMUSG00000090210
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A630048L14
Expression
Broad expression in limb E14.5 (RPKM 8.9), CNS E14 (RPKM 2.3) and 21 other tissues See more
Orthologs

Genomic context

See Itga10 in Genome Data Viewer
Location:
3; 3 F2.1
Exon count:
30
Annotation release Status Assembly Chr Location
108.20200622 current GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96645584..96664519)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (96449507..96468442)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein 8a Neighboring gene peroxisomal biogenesis factor 11 beta Neighboring gene ribosomal protein L21, pseudogene 11 Neighboring gene ankyrin repeat domain 35

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Potential readthrough

Included gene: Pex11b

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
collagen binding involved in cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
integrin-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
integrin alpha10-beta1 complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
integrin alpha-10
Names
integrin subunit alpha10

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001302471.1NP_001289400.1  integrin alpha-10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC112261, AC122037
    Consensus CDS
    CCDS38557.2
    UniProtKB/TrEMBL
    E9PXZ3
    Related
    ENSMUSP00000112393.1, ENSMUST00000119365.7
    Conserved Domains (3) summary
    smart00191
    Location:545599
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:166346
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6421049
    Integrin_alpha2; Integrin alpha

RefSeqs of Annotated Genomes: Mus musculus Updated Annotation Release 108.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p6 C57BL/6J

    Range
    96645584..96664519
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001081053.1: Suppressed sequence

    Description
    NM_001081053.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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