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Ifitm6 interferon induced transmembrane protein 6 [ Mus musculus (house mouse) ]

Gene ID: 213002, updated on 26-Sep-2022

Summary

Official Symbol
Ifitm6provided by MGI
Official Full Name
interferon induced transmembrane protein 6provided by MGI
Primary source
MGI:MGI:2686976
See related
Ensembl:ENSMUSG00000059108 AllianceGenome:MGI:2686976
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fgls5; Dspa2f; fragilis5; A330075D07
Summary
Predicted to be involved in several processes, including defense response to other organism; negative regulation of viral entry into host cell; and negative regulation of viral genome replication. Predicted to be active in plasma membrane. Is expressed in embryo; lung; musculature; and spleen. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver E18 (RPKM 126.8), spleen adult (RPKM 15.1) and 3 other tissues See more
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Genomic context

See Ifitm6 in Genome Data Viewer
Location:
7; 7 F5
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (140595725..140596805, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (141015812..141016892, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33504 Neighboring gene interferon induced transmembrane protein 3 Neighboring gene predicted gene, 39114 Neighboring gene beta-1,4-N-acetyl-galactosaminyl transferase 4 Neighboring gene plakophilin 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

General gene information

Markers

Clone Names

  • MGC129398, MGC129399

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in defense response to virus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of viral entry into host cell IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of viral genome replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in response to interferon-alpha IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in response to interferon-beta IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in response to type II interferon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in type I interferon-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
interferon induced transmembrane protein 6
Names
fragilis 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033632.1NP_001028804.1  interferon induced transmembrane protein 6

    See identical proteins and their annotated locations for NP_001028804.1

    Status: PROVISIONAL

    Source sequence(s)
    BC104338
    Consensus CDS
    CCDS21997.1
    UniProtKB/TrEMBL
    Q3SXF0
    Related
    ENSMUSP00000080594.4, ENSMUST00000081924.5
    Conserved Domains (1) summary
    pfam04505
    Location:2589
    CD225; Interferon-induced transmembrane protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    140595725..140596805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)