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Frat2 frequently rearranged in advanced T cell lymphomas 2 [ Mus musculus (house mouse) ]

Gene ID: 212398, updated on 26-Sep-2022

Summary

Official Symbol
Frat2provided by MGI
Official Full Name
frequently rearranged in advanced T cell lymphomas 2provided by MGI
Primary source
MGI:MGI:2673967
See related
Ensembl:ENSMUSG00000047604 AllianceGenome:MGI:2673967
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Acts upstream of or within Wnt signaling pathway. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human FRAT2 (FRAT regulator of WNT signaling pathway 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Frat2 in Genome Data Viewer
Location:
19 C3; 19 35.33 cM
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (41834411..41836571, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (41845972..41848132, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41847 Neighboring gene frequently rearranged in advanced T cell lymphomas Neighboring gene ribosomal RNA processing 12 homolog Neighboring gene predicted gene, 46644

Genomic regions, transcripts, and products

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC37615

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
GSK-3-binding protein FRAT2
Names
FRAT-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177603.3NP_808271.1  GSK-3-binding protein FRAT2

    See identical proteins and their annotated locations for NP_808271.1

    Status: VALIDATED

    Source sequence(s)
    AK081171, BC085510
    Consensus CDS
    CCDS29813.1
    UniProtKB/Swiss-Prot
    Q8K025
    Related
    ENSMUSP00000052788.3, ENSMUST00000059231.4
    Conserved Domains (1) summary
    pfam05350
    Location:1209
    GSK-3_bind; Glycogen synthase kinase-3 binding

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    41834411..41836571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)