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Tfdp2 transcription factor Dp 2 [ Mus musculus (house mouse) ]

Gene ID: 211586, updated on 9-Mar-2023

Summary

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Official Symbol
Tfdp2provided by MGI
Official Full Name
transcription factor Dp 2provided by MGI
Primary source
MGI:MGI:107167
See related
Ensembl:ENSMUSG00000032411 AllianceGenome:MGI:107167
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
DP3; DP-3; 1110029I05Rik; A330080J22Rik
Summary
Enables DNA-binding transcription factor activity. Acts upstream of or within regulation of transcription, DNA-templated. Predicted to be located in mitotic spindle and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and sensory organ. Orthologous to human TFDP2 (transcription factor Dp-2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 17.0), liver E14.5 (RPKM 15.8) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Tfdp2 in Genome Data Viewer
Location:
9; 9 E3.3
Exon count:
19
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (96078299..96205699)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (96196246..96323646)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 16794 Neighboring gene 5'-3' exoribonuclease 1 Neighboring gene glycerol kinase 5 (putative) Neighboring gene predicted gene, 39408 Neighboring gene ATPase, Na+/K+ transporting, beta 3 polypeptide Neighboring gene predicted gene, 39409 Neighboring gene predicted gene, 40550

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Global analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis. Chen C, et al. Exp Hematol, 2014 Jun. PMID 24607859, Free PMC Article
  2. A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F. Ormondroyd E, et al. Oncogene, 1995 Oct 19. PMID 7478568
  3. Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells. Wu L, et al. Front Immunol, 2020. PMID 33664736, Free PMC Article
  4. Dp1 is largely dispensable for embryonic development. Kohn MJ, et al. Mol Cell Biol, 2004 Aug. PMID 15282318, Free PMC Article
  5. Genomic structure and developmental expression of the mouse cell cycle regulatory transcription factor DP1. Gopalkrishnan RV, et al. Oncogene, 1996 Dec 19. PMID 9000141

See all (38) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells.
    Title: Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells.
  2. TFDP2 is a critical cofactor required for proper cell cycle control and gene expression
    Title: Global analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
contributes_to DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein domain specific binding ISO
Inferred from Sequence Orthology
more info
  
enables transcription factor binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase II transcription regulator complex ISO
Inferred from Sequence Orthology
more info
  
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear envelope TAS
Traceable Author Statement
more info
 PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
part_of transcription regulator complex IC
Inferred by Curator
more info
 PubMed 

General protein information

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Preferred Names
transcription factor Dp-2
Names
E2F dimerization partner 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001184706.2 → NP_001171635.1  transcription factor Dp-2 isoform 1

    See identical proteins and their annotated locations for NP_001171635.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (1, also known as A).
    Source sequence(s)
    AC117248, AC166175
    Consensus CDS
    CCDS23413.1
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3, Q8BHD2, Q8C8M7
    Related
    ENSMUSP00000034982.10, ENSMUST00000034982.16
    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  2. NM_001184708.2 → NP_001171637.1  transcription factor Dp-2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks several alternate exon and uses a downstream start codon, compared to variant 1. The resulting isoform (2, also known as B) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC117248, AC166175
    Consensus CDS
    CCDS52893.1
    UniProtKB/TrEMBL
    E9PWL5, Q8BHD2, Q8C8M7
    Related
    ENSMUSP00000132934.3, ENSMUST00000165120.9
    Conserved Domains (3) summary
    cd14458
    Location:77 → 123
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:1 → 72
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:79 → 218
    DP; Transcription factor DP

  3. NM_001184709.1 → NP_001171638.1  transcription factor Dp-2 isoform 1

    See identical proteins and their annotated locations for NP_001171638.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (1, also known as A).
    Source sequence(s)
    AC117248, AK033356, CJ141709
    Consensus CDS
    CCDS23413.1
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3, Q8BHD2
    Related
    ENSMUSP00000137176.2, ENSMUST00000179416.8
    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  4. NM_001184710.2 → NP_001171639.1  transcription factor Dp-2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) represents use of an alternate promoter, differs in the 5' UTR, lacks an alternate exon, and uses a downstream start codon, compared to variant 1. The resulting isoform (3, also known as C) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC117248, AC166175
    Consensus CDS
    CCDS52892.1
    UniProtKB/TrEMBL
    J3QK26, Q3TY79
    Related
    ENSMUSP00000136817.2, ENSMUST00000179065.8
    Conserved Domains (3) summary
    cd14458
    Location:126 → 172
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:42 → 121
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:128 → 267
    DP; Transcription factor DP

  5. NM_001184711.2 → NP_001171640.1  transcription factor Dp-2 isoform 4

    See identical proteins and their annotated locations for NP_001171640.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) represents use of an alternate promoter, differs in the 5' UTR, and uses an alternate in-frame splice site in the coding region, compared to variant 1. The resulting isoform (4, also known as D) includes an extra one amino acid segment, compared to isoform 1.
    Source sequence(s)
    AC117248, AC166175
    Consensus CDS
    CCDS57690.1
    UniProtKB/TrEMBL
    F6QG91, Q56A02
    Related
    ENSMUSP00000128260.3, ENSMUST00000165768.4
    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  6. NM_001408517.1 → NP_001395446.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  7. NM_001408518.1 → NP_001395447.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  8. NM_001408519.1 → NP_001395448.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  9. NM_001408520.1 → NP_001395449.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  10. NM_001408521.1 → NP_001395450.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  11. NM_001408522.1 → NP_001395451.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  12. NM_001408523.1 → NP_001395452.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  13. NM_001408524.1 → NP_001395453.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  14. NM_001408525.1 → NP_001395454.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  15. NM_001408526.1 → NP_001395455.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  16. NM_001408527.1 → NP_001395456.1  transcription factor Dp-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3

  17. NM_001408528.1 → NP_001395457.1  transcription factor Dp-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    E9PWL5

  18. NM_001408529.1 → NP_001395458.1  transcription factor Dp-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    E9PWL5

  19. NM_001408530.1 → NP_001395459.1  transcription factor Dp-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    E9PWL5

  20. NM_001408531.1 → NP_001395460.1  transcription factor Dp-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    E9PWL5

  21. NM_001408532.1 → NP_001395461.1  transcription factor Dp-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    E9PWL5

  22. NM_001408533.1 → NP_001395462.1  transcription factor Dp-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    E9PWL5

  23. NM_001408534.1 → NP_001395463.1  transcription factor Dp-2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    J3QK26

  24. NM_001408535.1 → NP_001395464.1  transcription factor Dp-2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    J3QK26

  25. NM_001408536.1 → NP_001395465.1  transcription factor Dp-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    F6QG91

  26. NM_001408537.1 → NP_001395466.1  transcription factor Dp-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    F6QG91

  27. NM_001408538.1 → NP_001395467.1  transcription factor Dp-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    F6QG91

  28. NM_001408539.1 → NP_001395468.1  transcription factor Dp-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    F6QG91

  29. NM_001408540.1 → NP_001395469.1  transcription factor Dp-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    F6QG91

  30. NM_001408541.1 → NP_001395470.1  transcription factor Dp-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    F6QG91

  31. NM_001408542.1 → NP_001395471.1  transcription factor Dp-2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    F6QG91

  32. NM_001408543.1 → NP_001395472.1  transcription factor Dp-2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  33. NM_001408544.1 → NP_001395473.1  transcription factor Dp-2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A087WPU8, A0A8C6HBY3

  34. NM_001408545.1 → NP_001395474.1  transcription factor Dp-2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  35. NM_001408546.1 → NP_001395475.1  transcription factor Dp-2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6HAI0

  36. NM_001408547.1 → NP_001395476.1  transcription factor Dp-2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  37. NM_001408548.1 → NP_001395477.1  transcription factor Dp-2 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175
    UniProtKB/TrEMBL
    A0A8C6H9K8

  38. NM_001408549.1 → NP_001395478.1  transcription factor Dp-2 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  39. NM_001408550.1 → NP_001395479.1  transcription factor Dp-2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  40. NM_001408551.1 → NP_001395480.1  transcription factor Dp-2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  41. NM_001408552.1 → NP_001395481.1  transcription factor Dp-2 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  42. NM_001408553.1 → NP_001395482.1  transcription factor Dp-2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  43. NM_001408554.1 → NP_001395483.1  transcription factor Dp-2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  44. NM_001408555.1 → NP_001395484.1  transcription factor Dp-2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  45. NM_001408556.1 → NP_001395485.1  transcription factor Dp-2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  46. NM_001408557.1 → NP_001395486.1  transcription factor Dp-2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  47. NM_001408558.1 → NP_001395487.1  transcription factor Dp-2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  48. NM_001408559.1 → NP_001395488.1  transcription factor Dp-2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  49. NM_001408560.1 → NP_001395489.1  transcription factor Dp-2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  50. NM_001408561.1 → NP_001395490.1  transcription factor Dp-2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  51. NM_001408562.1 → NP_001395491.1  transcription factor Dp-2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  52. NM_001408563.1 → NP_001395492.1  transcription factor Dp-2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  53. NM_001408564.1 → NP_001395493.1  transcription factor Dp-2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  54. NM_001408565.1 → NP_001395494.1  transcription factor Dp-2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  55. NM_001408566.1 → NP_001395495.1  transcription factor Dp-2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  56. NM_001408567.1 → NP_001395496.1  transcription factor Dp-2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  57. NM_001408568.1 → NP_001395497.1  transcription factor Dp-2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  58. NM_001408569.1 → NP_001395498.1  transcription factor Dp-2 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  59. NM_001408570.1 → NP_001395499.1  transcription factor Dp-2 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  60. NM_001408571.1 → NP_001395500.1  transcription factor Dp-2 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  61. NM_001408572.1 → NP_001395501.1  transcription factor Dp-2 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  62. NM_001408573.1 → NP_001395502.1  transcription factor Dp-2 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  63. NM_001408574.1 → NP_001395503.1  transcription factor Dp-2 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  64. NM_001408575.1 → NP_001395504.1  transcription factor Dp-2 isoform 21

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  65. NM_001408576.1 → NP_001395505.1  transcription factor Dp-2 isoform 22

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  66. NM_001408577.1 → NP_001395506.1  transcription factor Dp-2 isoform 22

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  67. NM_001408578.1 → NP_001395507.1  transcription factor Dp-2 isoform 22

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  68. NM_001408579.1 → NP_001395508.1  transcription factor Dp-2 isoform 22

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  69. NM_001408580.1 → NP_001395509.1  transcription factor Dp-2 isoform 23

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  70. NM_001408581.1 → NP_001395510.1  transcription factor Dp-2 isoform 23

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  71. NM_001408582.1 → NP_001395511.1  transcription factor Dp-2 isoform 23

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  72. NM_001408583.1 → NP_001395512.1  transcription factor Dp-2 isoform 23

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  73. NM_001408584.1 → NP_001395513.1  transcription factor Dp-2 isoform 23

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  74. NM_001408585.1 → NP_001395514.1  transcription factor Dp-2 isoform 24

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  75. NM_001408586.1 → NP_001395515.1  transcription factor Dp-2 isoform 25

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  76. NM_001408587.1 → NP_001395516.1  transcription factor Dp-2 isoform 25

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  77. NM_001408588.1 → NP_001395517.1  transcription factor Dp-2 isoform 25

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  78. NM_001408589.1 → NP_001395518.1  transcription factor Dp-2 isoform 25

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  79. NM_001408590.1 → NP_001395519.1  transcription factor Dp-2 isoform 25

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  80. NM_001408591.1 → NP_001395520.1  transcription factor Dp-2 isoform 26

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  81. NM_001408592.1 → NP_001395521.1  transcription factor Dp-2 isoform 26

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  82. NM_001408593.1 → NP_001395522.1  transcription factor Dp-2 isoform 26

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  83. NM_001408594.1 → NP_001395523.1  transcription factor Dp-2 isoform 27

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  84. NM_001408595.1 → NP_001395524.1  transcription factor Dp-2 isoform 27

    Status: VALIDATED

    Source sequence(s)
    AC117248, AC166175

  85. NM_178667.5 → NP_848782.2  transcription factor Dp-2 isoform 1

    See identical proteins and their annotated locations for NP_848782.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1, also known as A. Variants 1, 2, and 3 all encode the same isoform.
    Source sequence(s)
    AC117248, AC166175
    Consensus CDS
    CCDS23413.1
    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3, Q8BHD2, Q8C537, Q8C8M7
    Related
    ENSMUSP00000140061.2, ENSMUST00000185644.7
    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    96078299..96205699
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030244195.1 → XP_030100055.1  transcription factor Dp-2 isoform X12

    Conserved Domains (3) summary
    cd14458
    Location:137 → 183
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:51 → 132
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:139 → 277
    DP; Transcription factor DP

  2. XM_006510962.5 → XP_006511025.1  transcription factor Dp-2 isoform X2

    UniProtKB/TrEMBL
    A0A087WPU8
    Related
    ENSMUSP00000139926.2, ENSMUST00000188750.7
    Conserved Domains (3) summary
    cd14458
    Location:213 → 259
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:128 → 208
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:215 → 353
    DP; Transcription factor DP

  3. XM_006510961.4 → XP_006511024.1  transcription factor Dp-2 isoform X1

    Conserved Domains (3) summary
    cd14458
    Location:214 → 260
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:128 → 209
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:216 → 354
    DP; Transcription factor DP

  4. XM_006510965.5 → XP_006511028.1  transcription factor Dp-2 isoform X4

    Conserved Domains (3) summary
    cd14458
    Location:197 → 243
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:112 → 192
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:199 → 337
    DP; Transcription factor DP

  5. XM_036154781.1 → XP_036010674.1  transcription factor Dp-2 isoform X11

    UniProtKB/TrEMBL
    A0A8C6H9J8, F7AYT3
    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  6. XM_006510976.5 → XP_006511039.1  transcription factor Dp-2 isoform X11

    UniProtKB/TrEMBL
    Q8BHD2
    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  7. XM_030244189.2 → XP_030100049.1  transcription factor Dp-2 isoform X13

    Conserved Domains (3) summary
    cd14458
    Location:136 → 182
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:52 → 131
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:138 → 276
    DP; Transcription factor DP

  8. XM_036154780.1 → XP_036010673.1  transcription factor Dp-2 isoform X13

    Conserved Domains (3) summary
    cd14458
    Location:136 → 182
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:52 → 131
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:138 → 276
    DP; Transcription factor DP

  9. XM_006510973.5 → XP_006511036.1  transcription factor Dp-2 isoform X10

    UniProtKB/TrEMBL
    F6QG91
    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  10. XM_006510963.4 → XP_006511026.1  transcription factor Dp-2 isoform X3

    Conserved Domains (3) summary
    cd14458
    Location:198 → 244
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:112 → 193
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:200 → 338
    DP; Transcription factor DP

  11. XM_030244191.2 → XP_030100051.1  transcription factor Dp-2 isoform X11

    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  12. XM_030244192.1 → XP_030100052.1  transcription factor Dp-2 isoform X11

    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  13. XM_030244197.1 → XP_030100057.1  transcription factor Dp-2 isoform X13

    Conserved Domains (3) summary
    cd14458
    Location:136 → 182
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:52 → 131
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:138 → 276
    DP; Transcription factor DP

  14. XM_030244184.1 → XP_030100044.1  transcription factor Dp-2 isoform X10

    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  15. XM_017313267.2 → XP_017168756.1  transcription factor Dp-2 isoform X13

    Conserved Domains (3) summary
    cd14458
    Location:136 → 182
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:52 → 131
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:138 → 276
    DP; Transcription factor DP

  16. XM_030244194.1 → XP_030100054.1  transcription factor Dp-2 isoform X12

    Conserved Domains (3) summary
    cd14458
    Location:137 → 183
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:51 → 132
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:139 → 277
    DP; Transcription factor DP

  17. XM_030244204.2 → XP_030100064.1  transcription factor Dp-2 isoform X16

    Conserved Domains (3) summary
    cd14458
    Location:100 → 146
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:15 → 95
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:102 → 240
    DP; Transcription factor DP

  18. XM_030244187.2 → XP_030100047.1  transcription factor Dp-2 isoform X12

    Conserved Domains (3) summary
    cd14458
    Location:137 → 183
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:51 → 132
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:139 → 277
    DP; Transcription factor DP

  19. XM_030244185.1 → XP_030100045.1  transcription factor Dp-2 isoform X11

    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  20. XM_036154783.1 → XP_036010676.1  transcription factor Dp-2 isoform X17

    Conserved Domains (1) summary
    pfam08781
    Location:98 → 228
    DP; Transcription factor DP

  21. XM_006510970.4 → XP_006511033.1  transcription factor Dp-2 isoform X10

    UniProtKB/TrEMBL
    F6QG91
    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  22. XM_036154779.1 → XP_036010672.1  transcription factor Dp-2 isoform X10

    UniProtKB/TrEMBL
    F6QG91
    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  23. XM_036154778.1 → XP_036010671.1  transcription factor Dp-2 isoform X10

    UniProtKB/TrEMBL
    F6QG91
    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  24. XM_017313266.2 → XP_017168755.1  transcription factor Dp-2 isoform X9

    Conserved Domains (2) summary
    pfam02319
    Location:128 → 161
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:175 → 305
    DP; Transcription factor DP

  25. XM_030244201.1 → XP_030100061.1  transcription factor Dp-2 isoform X15

    Conserved Domains (3) summary
    cd14458
    Location:101 → 147
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:16 → 96
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:103 → 241
    DP; Transcription factor DP

  26. XM_006510971.4 → XP_006511034.1  transcription factor Dp-2 isoform X10

    UniProtKB/TrEMBL
    F6QG91
    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  27. XM_030244202.1 → XP_030100062.1  transcription factor Dp-2 isoform X15

    Conserved Domains (3) summary
    cd14458
    Location:101 → 147
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:16 → 96
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:103 → 241
    DP; Transcription factor DP

  28. XM_006510981.4 → XP_006511044.1  transcription factor Dp-2 isoform X15

    See identical proteins and their annotated locations for XP_006511044.1

    Conserved Domains (3) summary
    cd14458
    Location:101 → 147
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:16 → 96
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:103 → 241
    DP; Transcription factor DP

  29. XM_006510978.4 → XP_006511041.1  transcription factor Dp-2 isoform X12

    Related
    ENSMUSP00000139848.2, ENSMUST00000188008.7
    Conserved Domains (3) summary
    cd14458
    Location:137 → 183
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:51 → 132
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:139 → 277
    DP; Transcription factor DP

  30. XM_006510964.3 → XP_006511027.1  transcription factor Dp-2 isoform X5

    Conserved Domains (3) summary
    cd14458
    Location:197 → 243
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:111 → 192
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:199 → 337
    DP; Transcription factor DP

  31. XM_006510966.3 → XP_006511029.1  transcription factor Dp-2 isoform X6

    Conserved Domains (3) summary
    cd14458
    Location:196 → 242
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:111 → 191
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:198 → 336
    DP; Transcription factor DP

  32. XM_006510967.3 → XP_006511030.1  transcription factor Dp-2 isoform X7

    Conserved Domains (3) summary
    cd14458
    Location:181 → 227
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:95 → 176
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:183 → 321
    DP; Transcription factor DP

  33. XM_006510968.3 → XP_006511031.1  transcription factor Dp-2 isoform X8

    Conserved Domains (3) summary
    cd14458
    Location:180 → 226
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:95 → 175
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:182 → 320
    DP; Transcription factor DP

  34. XM_006510974.3 → XP_006511037.1  transcription factor Dp-2 isoform X10

    See identical proteins and their annotated locations for XP_006511037.1

    UniProtKB/TrEMBL
    F6QG91
    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  35. XM_030244193.1 → XP_030100053.1  transcription factor Dp-2 isoform X11

    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  36. XM_006510975.4 → XP_006511038.1  transcription factor Dp-2 isoform X10

    UniProtKB/TrEMBL
    F6QG91
    Conserved Domains (3) summary
    cd14458
    Location:153 → 199
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 148
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:155 → 293
    DP; Transcription factor DP

  37. XM_030244186.1 → XP_030100046.1  transcription factor Dp-2 isoform X11

    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  38. XM_030244200.1 → XP_030100060.1  transcription factor Dp-2 isoform X14

    Conserved Domains (2) summary
    pfam02319
    Location:67 → 100
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:114 → 244
    DP; Transcription factor DP

  39. XM_030244188.1 → XP_030100048.1  transcription factor Dp-2 isoform X12

    Related
    ENSMUSP00000141084.2, ENSMUST00000189606.7
    Conserved Domains (3) summary
    cd14458
    Location:137 → 183
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:51 → 132
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:139 → 277
    DP; Transcription factor DP

  40. XM_030244190.1 → XP_030100050.1  transcription factor Dp-2 isoform X13

    Conserved Domains (3) summary
    cd14458
    Location:136 → 182
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:52 → 131
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:138 → 276
    DP; Transcription factor DP

  41. XM_036154782.1 → XP_036010675.1  transcription factor Dp-2 isoform X15

    Conserved Domains (3) summary
    cd14458
    Location:101 → 147
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:16 → 96
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:103 → 241
    DP; Transcription factor DP

  42. XM_030244198.2 → XP_030100058.1  transcription factor Dp-2 isoform X13

    Conserved Domains (3) summary
    cd14458
    Location:136 → 182
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:52 → 131
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:138 → 276
    DP; Transcription factor DP

  43. XM_030244199.2 → XP_030100059.1  transcription factor Dp-2 isoform X14

    Conserved Domains (2) summary
    pfam02319
    Location:67 → 100
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:114 → 244
    DP; Transcription factor DP

  44. XM_006510979.4 → XP_006511042.1  transcription factor Dp-2 isoform X12

    Conserved Domains (3) summary
    cd14458
    Location:137 → 183
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:51 → 132
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:139 → 277
    DP; Transcription factor DP

  45. XM_006510977.4 → XP_006511040.1  transcription factor Dp-2 isoform X11

    UniProtKB/TrEMBL
    Q8BHD2
    Conserved Domains (3) summary
    cd14458
    Location:152 → 198
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:68 → 147
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:154 → 292
    DP; Transcription factor DP

  46. XM_030244203.2 → XP_030100063.1  transcription factor Dp-2 isoform X15

    Conserved Domains (3) summary
    cd14458
    Location:101 → 147
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:16 → 96
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:103 → 241
    DP; Transcription factor DP

  47. XM_030244205.2 → XP_030100065.1  transcription factor Dp-2 isoform X16

    Conserved Domains (3) summary
    cd14458
    Location:100 → 146
    DP_DD; coiled coil [structural motif]
    pfam02319
    Location:15 → 95
    E2F_TDP; E2F/DP family winged-helix DNA-binding domain
    pfam08781
    Location:102 → 240
    DP; Transcription factor DP
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q64163.2 GenPept UniProtKB/Swiss-Prot:Q64163

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