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Exoc3 exocyst complex component 3 [ Mus musculus (house mouse) ]

Gene ID: 211446, updated on 28-May-2024

Summary

Official Symbol
Exoc3provided by MGI
Official Full Name
exocyst complex component 3provided by MGI
Primary source
MGI:MGI:2443972
See related
Ensembl:ENSMUSG00000034152 AllianceGenome:MGI:2443972
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sec6; Sec6l1; 2810050O03Rik; E430013E20Rik
Summary
Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Predicted to act upstream of or within protein transport. Predicted to be located in secretory granule membrane. Predicted to be part of exocyst. Orthologous to human EXOC3 (exocyst complex component 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 10.0), CNS E11.5 (RPKM 9.6) and 28 other tissues See more
Orthologs
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Genomic context

See Exoc3 in Genome Data Viewer
Location:
13 C1; 13 40.15 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (74317921..74358151, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (74169802..74210032, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene centrosomal protein 72 Neighboring gene solute carrier family 9 (sodium/hydrogen exchanger), member 3 Neighboring gene predicted gene, 41003 Neighboring gene STARR-positive B cell enhancer ABC_E8534 Neighboring gene aryl-hydrocarbon receptor repressor Neighboring gene programmed cell death 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in exocyst localization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in membrane fission NAS
Non-traceable Author Statement
more info
PubMed 
involved_in mitotic cytokinesis NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle docking involved in exocytosis NAS
Non-traceable Author Statement
more info
PubMed 
involved_in vesicle tethering involved in exocytosis NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of exocyst NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in presynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
located_in secretory granule membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
exocyst complex component 3
Names
SEC6-like 1
exocyst complex component Sec6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177333.4NP_796307.2  exocyst complex component 3

    See identical proteins and their annotated locations for NP_796307.2

    Status: VALIDATED

    Source sequence(s)
    AC123833, AC154839
    Consensus CDS
    CCDS26640.1
    UniProtKB/Swiss-Prot
    Q6KAR6
    UniProtKB/TrEMBL
    Q8BIT7, Q8K0E2
    Related
    ENSMUSP00000039416.6, ENSMUST00000035934.7
    Conserved Domains (1) summary
    pfam06046
    Location:187743
    Sec6; Exocyst complex component Sec6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    74317921..74358151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517191.4XP_006517254.1  exocyst complex component 3 isoform X1

    See identical proteins and their annotated locations for XP_006517254.1

    UniProtKB/Swiss-Prot
    Q6KAR6
    UniProtKB/TrEMBL
    Q8BIT7, Q8K0E2
    Conserved Domains (1) summary
    pfam06046
    Location:187743
    Sec6; Exocyst complex component Sec6
  2. XM_006517192.3XP_006517255.1  exocyst complex component 3 isoform X2

    UniProtKB/TrEMBL
    Q8BIT7
    Conserved Domains (1) summary
    pfam06046
    Location:187657
    Sec6; Exocyst complex component Sec6
  3. XM_017315474.3XP_017170963.1  exocyst complex component 3 isoform X2

    UniProtKB/TrEMBL
    Q8BIT7
    Conserved Domains (1) summary
    pfam06046
    Location:187657
    Sec6; Exocyst complex component Sec6