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Sectm1a secreted and transmembrane 1A [ Mus musculus (house mouse) ]

Gene ID: 209588, updated on 8-Feb-2024

Summary

Official Symbol
Sectm1aprovided by MGI
Official Full Name
secreted and transmembrane 1Aprovided by MGI
Primary source
MGI:MGI:2384805
See related
Ensembl:ENSMUSG00000025165 AllianceGenome:MGI:2384805
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable cytokine activity. Predicted to be involved in immune response. Predicted to be located in extracellular region and plasma membrane. Predicted to be integral component of membrane. Is expressed in cortical plate. Orthologous to human SECTM1 (secreted and transmembrane 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 2.8), colon adult (RPKM 2.3) and 17 other tissues See more
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Genomic context

See Sectm1a in Genome Data Viewer
Location:
11 E2; 11 84.89 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (120958221..120988023, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (121067395..121097153, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11775 Neighboring gene CD7 antigen Neighboring gene secreted and transmembrane 1B Neighboring gene predicted gene 11793 Neighboring gene testis expressed gene 19.2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1)  1 citation

General gene information

Clone Names

  • MGC7970

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
secreted and transmembrane protein 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145373.2NP_663348.2  secreted and transmembrane protein 1A precursor

    See identical proteins and their annotated locations for NP_663348.2

    Status: VALIDATED

    Source sequence(s)
    AK082020, AL662887, AW985540
    Consensus CDS
    CCDS25766.1
    UniProtKB/Swiss-Prot
    Q921W8
    UniProtKB/TrEMBL
    A2ABP9
    Related
    ENSMUSP00000026162.6, ENSMUST00000026162.12

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    120958221..120988023 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532748.5XP_006532811.1  secreted and transmembrane protein 1A isoform X1

    See identical proteins and their annotated locations for XP_006532811.1

    UniProtKB/Swiss-Prot
    Q921W8
    UniProtKB/TrEMBL
    A2ABP9
  2. XM_017314413.1XP_017169902.1  secreted and transmembrane protein 1A isoform X1

    UniProtKB/Swiss-Prot
    Q921W8
    UniProtKB/TrEMBL
    A2ABP9
  3. XM_036156494.1XP_036012387.1  secreted and transmembrane protein 1A isoform X2

    UniProtKB/Swiss-Prot
    Q921W8
    UniProtKB/TrEMBL
    A2ABP7
    Related
    ENSMUSP00000101726.3, ENSMUST00000106120.3
  4. XM_017314414.1XP_017169903.1  secreted and transmembrane protein 1A isoform X3