U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Surf4 surfeit gene 4 [ Mus musculus (house mouse) ]

Gene ID: 20932, updated on 30-Oct-2022

Summary

Official Symbol
Surf4provided by MGI
Official Full Name
surfeit gene 4provided by MGI
Primary source
MGI:MGI:98445
See related
Ensembl:ENSMUSG00000014867 AllianceGenome:MGI:98445
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Surf-4
Summary
Predicted to be involved in Golgi organization and positive regulation of organelle organization. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment. Is expressed in embryo and pancreas tip epithelium. Orthologous to human SURF4 (surfeit 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in duodenum adult (RPKM 218.1), large intestine adult (RPKM 165.7) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Surf4 in Genome Data Viewer
Location:
2 A3; 2 19.1 cM
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26810053..26823793, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26920041..26933776, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD36 Neighboring gene ribosomal protein L7A Neighboring gene surfeit gene 1 Neighboring gene surfeit gene 2 Neighboring gene predicted gene, 36591 Neighboring gene serine/threonine kinase-like domain containing 1 Neighboring gene REX4, 3'-5' exonuclease Neighboring gene predicted gene, 36649 Neighboring gene a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cargo receptor activity ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
 
involved_in lipid homeostasis ISO
Inferred from Sequence Orthology
more info
 
involved_in lipoprotein transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of organelle organization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of lipid transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum-Golgi intermediate compartment ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011512.3NP_035642.1  surfeit locus protein 4

    See identical proteins and their annotated locations for NP_035642.1

    Status: VALIDATED

    Source sequence(s)
    AK145670, BB854341, DV656434
    Consensus CDS
    CCDS15817.1
    UniProtKB/Swiss-Prot
    Q64310
    UniProtKB/TrEMBL
    A0A8C6HJD0, Q545Q2
    Related
    ENSMUSP00000015011.4, ENSMUST00000015011.10
    Conserved Domains (1) summary
    pfam02077
    Location:4269
    SURF4; SURF4 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    26810053..26823793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497828.4XP_006497891.1  surfeit locus protein 4 isoform X1

    See identical proteins and their annotated locations for XP_006497891.1

    Conserved Domains (1) summary
    cl21527
    Location:1226
    DoxX