U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Osgin2 oxidative stress induced growth inhibitor family member 2 [ Mus musculus (house mouse) ]

Gene ID: 209212, updated on 26-Sep-2022

Summary

Go to the top of the page Help
Official Symbol
Osgin2provided by MGI
Official Full Name
oxidative stress induced growth inhibitor family member 2provided by MGI
Primary source
MGI:MGI:2384798
See related
Ensembl:ENSMUSG00000041153 AllianceGenome:MGI:2384798
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C230027H09Rik
Summary
Predicted to enable growth factor activity. Predicted to be involved in negative regulation of cell growth. Is expressed in dorsal root ganglion; medulla oblongata basal plate mantle layer; and trigeminal ganglion. Orthologous to human OSGIN2 (oxidative stress induced growth inhibitor family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 3.0), cerebellum adult (RPKM 2.7) and 26 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Osgin2 in Genome Data Viewer
Location:
4; 4 A2
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (15996354..16015266, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (15996354..16015258, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene 2,4-dienoyl CoA reductase 1, mitochondrial Neighboring gene microRNA 6400 Neighboring gene nibrin Neighboring gene receptor (TNFRSF)-interacting serine-threonine kinase 2 Neighboring gene RIKEN cDNA gene A530072M11 Neighboring gene mortality factor 4 like 2 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
  2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC11786

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables growth factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell growth IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
oxidative stress-induced growth inhibitor 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355615.1 → NP_001342544.1  oxidative stress-induced growth inhibitor 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK048731, AK148243, AL807737, BM949030, CJ182959, CJ313585
    Conserved Domains (1) summary
    cl21454
    Location:118 → 339
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. NM_001355616.1 → NP_001342545.1  oxidative stress-induced growth inhibitor 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK048731, AK148243, AL807737, BM949030, BP765138, CJ313585
    Conserved Domains (1) summary
    cl21454
    Location:5 → 206
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. NM_145950.5 → NP_666062.3  oxidative stress-induced growth inhibitor 2 isoform 1

    See identical proteins and their annotated locations for NP_666062.3

    Status: VALIDATED

    Source sequence(s)
    AK048731, AK148243, AL807737, BM949030, CJ313585
    Consensus CDS
    CCDS17987.1
    UniProtKB/TrEMBL
    Q3TEE9
    Related
    ENSMUSP00000047473.4, ENSMUST00000037198.10
    Conserved Domains (1) summary
    cl21454
    Location:217 → 378
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    15996354..16015266 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253377.2 → XP_030109237.1  oxidative stress-induced growth inhibitor 2 isoform X2

    Conserved Domains (1) summary
    cl21454
    Location:5 → 206
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  2. XM_006537728.5 → XP_006537791.1  oxidative stress-induced growth inhibitor 2 isoform X1

    See identical proteins and their annotated locations for XP_006537791.1

    Conserved Domains (1) summary
    cl21454
    Location:118 → 339
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous