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Samd9l sterile alpha motif domain containing 9-like [ Mus musculus (house mouse) ]

Gene ID: 209086, updated on 6-Nov-2022

Summary

Official Symbol
Samd9lprovided by MGI
Official Full Name
sterile alpha motif domain containing 9-likeprovided by MGI
Primary source
MGI:MGI:1343184
See related
Ensembl:ENSMUSG00000047735 AllianceGenome:MGI:1343184
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ESTM25; mKIAA2005
Summary
Acts upstream of or within several processes, including common myeloid progenitor cell proliferation; endosomal vesicle fusion; and hematopoietic or lymphoid organ development. Located in early endosome. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and liver and biliary system. Used to study myelodysplastic syndrome. Orthologous to human SAMD9L (sterile alpha motif domain containing 9 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney adult (RPKM 4.1), bladder adult (RPKM 3.7) and 22 other tissues See more
Orthologs
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Genomic context

See Samd9l in Genome Data Viewer
Location:
6 A1; 6 1.76 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (3372257..3399571, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (3372257..3399571, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 384 pseudogene Neighboring gene predicted gene, 20559 Neighboring gene HEPACAM family member 2 Neighboring gene VPS50 EARP/GARPII complex subunit Neighboring gene predicted gene, 52885

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (3) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
sterile alpha motif domain-containing protein 9-like
Names
SAM domain-containing protein 9-like
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010156.3NP_034286.2  sterile alpha motif domain-containing protein 9-like

    See identical proteins and their annotated locations for NP_034286.2

    Status: VALIDATED

    Source sequence(s)
    AK035419, AK052535, BC079894
    Consensus CDS
    CCDS51712.1
    UniProtKB/TrEMBL
    E9PX59, Q8BZG4
    Related
    ENSMUSP00000112688.2, ENSMUST00000120087.6
    Conserved Domains (1) summary
    cd09528
    Location:1276
    SAM_Samd9_Samd9L; SAM domain of Samd9/Samd9L subfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    3372257..3399571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505026.3XP_006505089.1  sterile alpha motif domain-containing protein 9-like isoform X1

    See identical proteins and their annotated locations for XP_006505089.1

    UniProtKB/TrEMBL
    E9PX59
    Conserved Domains (1) summary
    cd09528
    Location:1276
    SAM_Samd9_Samd9L; SAM domain of Samd9/Samd9L subfamily

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_177590.1: Suppressed sequence

    Description
    NM_177590.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.