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Zfp976 zinc finger protein 976 [ Mus musculus (house mouse) ]

Gene ID: 208111, updated on 2-Nov-2024

Summary

Official Symbol
Zfp976provided by MGI
Official Full Name
zinc finger protein 976provided by MGI
Primary source
MGI:MGI:3036263
See related
Ensembl:ENSMUSG00000074158 AllianceGenome:MGI:3036263
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9830147E19Rik; C330019L16Rik
Summary
Predicted to enable DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and protein-macromolecule adaptor activity. Acts upstream of or within cellular response to heat. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to several human genes including ZNF14 (zinc finger protein 14); ZNF234 (zinc finger protein 234); and ZNF254 (zinc finger protein 254). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Zfp976 in Genome Data Viewer
Location:
7 B3; 7 28.25 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (42258938..42293684, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (42609514..42644267, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18740 Neighboring gene STARR-seq mESC enhancer starr_18741 Neighboring gene predicted gene, 53386 Neighboring gene STARR-seq mESC enhancer starr_18742 Neighboring gene STARR-seq mESC enhancer starr_18744 Neighboring gene predicted gene, 21028 Neighboring gene zinc finger protein 977 Neighboring gene STARR-seq mESC enhancer starr_18745 Neighboring gene zinc finger protein 975 Neighboring gene STARR-seq mESC enhancer starr_18747 Neighboring gene predicted gene, 38998

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to heat IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242388.1NP_001229317.1  zinc finger protein-like

    Status: VALIDATED

    Source sequence(s)
    AC102628, AK141688, BP762393
    Consensus CDS
    CCDS57543.1
    UniProtKB/TrEMBL
    E9Q981
    Related
    ENSMUSP00000096105.3, ENSMUST00000098503.9
    Conserved Domains (5) summary
    smart00349
    Location:445
    KRAB; krueppel associated box
    COG5048
    Location:156530
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:553573
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:441
    KRAB; KRAB box
    pfam13465
    Location:481506
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    42258938..42293684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017322075.3XP_017177564.1  zinc finger protein-like isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:221595
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:590610
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:69109
    KRAB; KRAB box
    pfam13465
    Location:602627
    zf-H2C2_2; Zinc-finger double domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001034857.3: Suppressed sequence

    Description
    NM_001034857.3: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.