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BC034090 cDNA sequence BC034090 [ Mus musculus (house mouse) ]

Gene ID: 207792, updated on 8-Dec-2022

Summary

Official Symbol
BC034090provided by MGI
Official Full Name
cDNA sequence BC034090provided by MGI
Primary source
MGI:MGI:2672904
See related
Ensembl:ENSMUSG00000033722 AllianceGenome:MGI:2672904
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1614; 6820428L09
Summary
Predicted to enable protein kinase C binding activity. Predicted to be involved in centrosome cycle; establishment or maintenance of cell polarity; and regulation of cellular localization. Predicted to be active in apical plasma membrane; cell cortex; and nucleus. Orthologous to human KIAA1614 (KIAA1614). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney adult (RPKM 13.3), adrenal adult (RPKM 6.5) and 19 other tissues See more
Orthologs
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Genomic context

See BC034090 in Genome Data Viewer
Location:
1; 1 G3
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (155088217..155123504, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (155212471..155245639, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30922 Neighboring gene major histocompatibility complex, class I-related Neighboring gene syntaxin 6 Neighboring gene high mobility group protein B3 pseudogene Neighboring gene predicted gene, 31102 Neighboring gene xenotropic and polytropic retrovirus receptor 1 Neighboring gene predicted gene, 17974 Neighboring gene predicted gene, 31713

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in centrosome cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in establishment or maintenance of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of cellular localization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
uncharacterized protein KIAA1614 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370865.1NP_001357794.1  uncharacterized protein KIAA1614 homolog

    Status: VALIDATED

    Source sequence(s)
    AC110268
    Consensus CDS
    CCDS87895.1
    UniProtKB/TrEMBL
    A0A087WP46
    Related
    ENSMUSP00000139623.2, ENSMUST00000186156.7
    Conserved Domains (2) summary
    cd00992
    Location:11141195
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:337461
    DUF4685; Domain of unknown function (DUF4685)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    155088217..155123504 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530031.5XP_006530094.1  uncharacterized protein KIAA1614 homolog isoform X2

    Conserved Domains (2) summary
    cd00992
    Location:10461127
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:337461
    DUF4685; Domain of unknown function (DUF4685)
  2. XM_148974.13XP_148974.3  uncharacterized protein KIAA1614 homolog isoform X1

    Conserved Domains (2) summary
    cd00992
    Location:10831164
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:306430
    DUF4685; Domain of unknown function (DUF4685)
  3. XM_030252447.1XP_030108307.1  uncharacterized protein KIAA1614 homolog isoform X3

    UniProtKB/TrEMBL
    F6T2X5
    Related
    ENSMUSP00000037456.5, ENSMUST00000035914.5
    Conserved Domains (2) summary
    cd00992
    Location:752833
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:199
    DUF4685; Domain of unknown function (DUF4685)
  4. XM_006530035.4XP_006530098.1  uncharacterized protein KIAA1614 homolog isoform X3

    UniProtKB/TrEMBL
    F6T2X5
    Conserved Domains (2) summary
    cd00992
    Location:752833
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:199
    DUF4685; Domain of unknown function (DUF4685)
  5. XM_036163040.1XP_036018933.1  uncharacterized protein KIAA1614 homolog isoform X3

    UniProtKB/TrEMBL
    F6T2X5
    Conserved Domains (2) summary
    cd00992
    Location:752833
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:199
    DUF4685; Domain of unknown function (DUF4685)
  6. XM_006530036.5XP_006530099.1  uncharacterized protein KIAA1614 homolog isoform X4

    Conserved Domains (2) summary
    cd00992
    Location:687768
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:134
    DUF4685; Domain of unknown function (DUF4685)
  7. XM_036163046.1XP_036018939.1  uncharacterized protein KIAA1614 homolog isoform X5

    Conserved Domains (2) summary
    cd00992
    Location:619700
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:134
    DUF4685; Domain of unknown function (DUF4685)

RNA

  1. XR_003954294.2 RNA Sequence

  2. XR_004941304.1 RNA Sequence

  3. XR_004941302.1 RNA Sequence

  4. XR_004941303.1 RNA Sequence

  5. XR_387502.5 RNA Sequence

  6. XR_878643.4 RNA Sequence