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Spr sepiapterin reductase [ Mus musculus (house mouse) ]

Gene ID: 20751, updated on 5-Aug-2018
Official Symbol
Sprprovided by MGI
Official Full Name
sepiapterin reductaseprovided by MGI
Primary source
MGI:MGI:103078
See related
Ensembl:ENSMUSG00000033735 Vega:OTTMUSG00000037795
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm10328; AA409688
Expression
Ubiquitous expression in kidney adult (RPKM 25.9), liver adult (RPKM 22.1) and 27 other tissues See more
Orthologs
See Spr in Genome Data Viewer
Location:
6 C3; 6 37.15 cM
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (85133680..85137764, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (85083674..85087758, complement)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene nucleoplasmin 3, pseudogene 1 Neighboring gene predicted gene 5878 Neighboring gene predicted pseudogene 10444 Neighboring gene sepiapterin reductase pseudogene 1

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
sepiapterin reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sepiapterin reductase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
L-phenylalanine metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell morphogenesis involved in neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
dopamine metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
nitric oxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
norepinephrine metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
pteridine metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to organic substance ISO
Inferred from Sequence Orthology
more info
 
serotonin metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
tetrahydrobiopterin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tetrahydrobiopterin biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
tetrahydrobiopterin metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
voluntary musculoskeletal movement IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
mitochondrion HDA PubMed 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
sepiapterin reductase
NP_035597.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011467.2NP_035597.2  sepiapterin reductase

    See identical proteins and their annotated locations for NP_035597.2

    Status: VALIDATED

    Source sequence(s)
    BY113096, BY590544, CK620382, W65601
    Consensus CDS
    CCDS51826.1
    UniProtKB/TrEMBL
    Q91XH5
    Related
    ENSMUSP00000048111.7, OTTMUSP00000054720, ENSMUST00000045986.7, OTTMUST00000097538
    Conserved Domains (2) summary
    pfam00106
    Location:10213
    adh_short; short chain dehydrogenase
    cl21454
    Location:9261
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    85133680..85137764 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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