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Zbtb7c zinc finger and BTB domain containing 7C [ Mus musculus (house mouse) ]

Gene ID: 207259, updated on 18-Apr-2024

Summary

Official Symbol
Zbtb7cprovided by MGI
Official Full Name
zinc finger and BTB domain containing 7Cprovided by MGI
Primary source
MGI:MGI:2443302
See related
Ensembl:ENSMUSG00000044646 AllianceGenome:MGI:2443302
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Kr-pok; Zbtb36; B230208J24Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of fat cell differentiation; positive regulation of transcription by RNA polymerase II; and regulation of RNA polymerase II regulatory region sequence-specific DNA binding activity. Located in nucleus. Is expressed in central nervous system; craniocervical region bone; esophagus; maturing glomerular tuft; and nose. Orthologous to human ZBTB7C (zinc finger and BTB domain containing 7C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in stomach adult (RPKM 11.5), colon adult (RPKM 6.0) and 21 other tissues See more
Orthologs
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Genomic context

Location:
18 E3; 18 51.1 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (75953249..76281635)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (75820178..76148564)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700034B16 gene Neighboring gene predicted gene, 33703 Neighboring gene STARR-seq mESC enhancer starr_45085 Neighboring gene STARR-seq mESC enhancer starr_45086 Neighboring gene predicted gene, 52362 Neighboring gene RIKEN cDNA 2900057B20 gene Neighboring gene STARR-seq mESC enhancer starr_45090 Neighboring gene predicted gene, 52361 Neighboring gene STARR-seq mESC enhancer starr_45092 Neighboring gene microRNA 6358 Neighboring gene predicted gene, 52360 Neighboring gene predicted gene 9028

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Gene trapped (1) 
  • Targeted (1)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 7C
Names
zinc finger and BTB domain containing 36
zinc finger and BTB domain-containing protein 36

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357506.2NP_001344435.1  zinc finger and BTB domain-containing protein 7C

    Status: VALIDATED

    Source sequence(s)
    AC107768
    Consensus CDS
    CCDS29349.1
    UniProtKB/Swiss-Prot
    Q8VCZ7
    Related
    ENSMUSP00000126808.2, ENSMUST00000167921.2
    Conserved Domains (3) summary
    COG5189
    Location:380468
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:394414
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18328
    Location:9128
    BTB_POZ_ZBTB7C_ZBTB36; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7C (ZBTB7C)
  2. NM_145356.3NP_663331.1  zinc finger and BTB domain-containing protein 7C

    See identical proteins and their annotated locations for NP_663331.1

    Status: VALIDATED

    Source sequence(s)
    BC070424
    Consensus CDS
    CCDS29349.1
    UniProtKB/Swiss-Prot
    Q8VCZ7
    Related
    ENSMUSP00000057856.8, ENSMUST00000058997.15
    Conserved Domains (3) summary
    COG5189
    Location:380468
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:394414
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18328
    Location:9128
    BTB_POZ_ZBTB7C_ZBTB36; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7C (ZBTB7C)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    75953249..76281635
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161041.1XP_036016934.1  zinc finger and BTB domain-containing protein 7C isoform X1

    Conserved Domains (3) summary
    COG5189
    Location:386474
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:400420
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18328
    Location:15134
    BTB_POZ_ZBTB7C_ZBTB36; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7C (ZBTB7C)
  2. XM_036161042.1XP_036016935.1  zinc finger and BTB domain-containing protein 7C isoform X2

    UniProtKB/Swiss-Prot
    Q8VCZ7
    Conserved Domains (3) summary
    COG5189
    Location:380468
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:394414
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18328
    Location:9128
    BTB_POZ_ZBTB7C_ZBTB36; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 7C (ZBTB7C)