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Snrpd1 small nuclear ribonucleoprotein D1 [ Mus musculus (house mouse) ]

Gene ID: 20641, updated on 1-Mar-2024

Summary

Official Symbol
Snrpd1provided by MGI
Official Full Name
small nuclear ribonucleoprotein D1provided by MGI
Primary source
MGI:MGI:98344
See related
Ensembl:ENSMUSG00000002477 AllianceGenome:MGI:98344
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SMD1
Summary
Predicted to enable RNA binding activity and U1 snRNP binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in connective tissue disease; nephritis; proteinuria; and systemic lupus erythematosus. Orthologous to human SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver E14 (RPKM 92.1), CNS E11.5 (RPKM 90.4) and 14 other tissues See more
Orthologs
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Genomic context

See Snrpd1 in Genome Data Viewer
Location:
18 A1; 18 5.25 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (10617796..10628230)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (10617796..10628230)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene growth regulation by estrogen in breast cancer-like Neighboring gene nuclear transport factor 2, pseudogene 2 Neighboring gene STARR-seq mESC enhancer starr_43798 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:10532920-10533103 Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 1 Neighboring gene abhydrolase domain containing 3 Neighboring gene RIKEN cDNA 4930563E18 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables U1 snRNP binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within RNA splicing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splicing, via spliceosome ISO
Inferred from Sequence Orthology
more info
 
involved_in spliceosomal snRNP assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in spliceosomal snRNP assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of SMN-Sm protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of SMN-Sm protein complex ISO
Inferred from Sequence Orthology
more info
 
part_of U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U1 snRNP ISO
Inferred from Sequence Orthology
more info
 
part_of U12-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U12-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U2-type catalytic step 2 spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type precatalytic spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of U2-type spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
part_of U4 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U4 snRNP ISO
Inferred from Sequence Orthology
more info
 
part_of U4/U6 x U5 tri-snRNP complex ISO
Inferred from Sequence Orthology
more info
 
part_of U5 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of catalytic step 2 spliceosome ISO
Inferred from Sequence Orthology
more info
 
part_of commitment complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of methylosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of pICln-Sm protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of pICln-Sm protein complex ISO
Inferred from Sequence Orthology
more info
 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex ISO
Inferred from Sequence Orthology
more info
 
part_of spliceosomal tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
small nuclear ribonucleoprotein Sm D1
Names
sm-D autoantigen
sm-D1
snRNP core protein D1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009226.4NP_033252.1  small nuclear ribonucleoprotein Sm D1

    See identical proteins and their annotated locations for NP_033252.1

    Status: PROVISIONAL

    Source sequence(s)
    AC105947
    Consensus CDS
    CCDS29056.1
    UniProtKB/Swiss-Prot
    P62315, Q3UYM0
    Related
    ENSMUSP00000002551.4, ENSMUST00000002551.5
    Conserved Domains (1) summary
    cd01724
    Location:293
    Sm_D1; Sm protein D1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    10617796..10628230
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)