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Slfn3 schlafen 3 [ Mus musculus (house mouse) ]

Gene ID: 20557, updated on 13-Feb-2024

Summary

Official Symbol
Slfn3provided by MGI
Official Full Name
schlafen 3provided by MGI
Primary source
MGI:MGI:1329005
See related
Ensembl:ENSMUSG00000018986 AllianceGenome:MGI:1329005
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Acts upstream of or within negative regulation of cell population proliferation. Is expressed in several structures, including alimentary system; genitourinary system; liver; sensory organ; and skeleton. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver E14 (RPKM 2.2), liver E14.5 (RPKM 1.6) and 19 other tissues See more
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Genomic context

See Slfn3 in Genome Data Viewer
Location:
11 C; 11 50.3 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (83082156..83105980)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (83191330..83215154)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38922 Neighboring gene STARR-seq mESC enhancer starr_30189 Neighboring gene schlafen 4 Neighboring gene STARR-positive B cell enhancer ABC_E3002 Neighboring gene STARR-positive B cell enhancer ABC_E1423 Neighboring gene STARR-positive B cell enhancer ABC_E10700 Neighboring gene STARR-seq mESC enhancer starr_30190 Neighboring gene schlafen long noncoding RNA Neighboring gene STARR-seq mESC enhancer starr_30191 Neighboring gene predicted gene, 38924

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA nuclease activity ISO
Inferred from Sequence Orthology
more info
 
enables ribosome binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011409.1NP_035539.1  schlafen 3

    See identical proteins and their annotated locations for NP_035539.1

    Status: VALIDATED

    Source sequence(s)
    AF099974
    Consensus CDS
    CCDS25159.1
    UniProtKB/TrEMBL
    A0A1G5SK74, A0A1G5SLM1, Q9Z0I5
    Related
    ENSMUSP00000019130.8, ENSMUST00000019130.8
    Conserved Domains (2) summary
    PHA02782
    Location:4305
    PHA02782; hypothetical protein; Provisional
    pfam04326
    Location:175298
    AlbA_2; Putative DNA-binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    83082156..83105980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)