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DIPK2A divergent protein kinase domain 2A [ Homo sapiens (human) ]

Gene ID: 205428, updated on 12-Oct-2019

Summary

Official Symbol
DIPK2Aprovided by HGNC
Official Full Name
divergent protein kinase domain 2Aprovided by HGNC
Primary source
HGNC:HGNC:28490
See related
Ensembl:ENSG00000181744 MIM:612200
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DIA1; HASF; C3orf58; GoPro49
Expression
Ubiquitous expression in placenta (RPKM 13.9), bone marrow (RPKM 9.8) and 24 other tissues See more
Orthologs

Genomic context

See DIPK2A in Genome Data Viewer
Location:
3q24
Exon count:
4
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (143971798..143992368)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (143690640..143711210)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene solute carrier family 9 member A9 Neighboring gene uncharacterized LOC102724120 Neighboring gene ribosomal protein S17 pseudogene 10 Neighboring gene uncharacterized LOC105374140 Neighboring gene RNA, 5S ribosomal pseudogene 144 Neighboring gene uncharacterized LOC105374139

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC33365

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cardiac muscle cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cardiac muscle cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of smooth muscle cell apoptotic process IEA
Inferred from Electronic Annotation
more info
 
regulation of phosphatidylinositol 3-kinase signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of phosphatidylinositol 3-kinase signaling IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
COPI vesicle coat IDA
Inferred from Direct Assay
more info
PubMed 
Golgi membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
divergent protein kinase domain 2A
Names
Golgi Protein of 49 kDa
Golgi protein GoPro49
UPF0672 protein C3orf58
deleted in autism 1
deleted in autism protein 1
hypoxia and AKT-induced stem cell factor
hypoxia and Akt induced stem cell factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134470.2NP_001127942.1  divergent protein kinase domain 2A isoform b

    See identical proteins and their annotated locations for NP_001127942.1

    Status: VALIDATED

    Source sequence(s)
    AK095400, BC037293, BM968874, DC310234, DC310421, DC323688
    Consensus CDS
    CCDS46929.1
    UniProtKB/Swiss-Prot
    Q8NDZ4
    UniProtKB/TrEMBL
    B3KTD4
    Related
    ENSP00000417382.1, ENST00000495414.5
    Conserved Domains (1) summary
    cl21453
    Location:11196
    PKc_like; Protein Kinases, catalytic domain
  2. NM_001363944.1NP_001350873.1  divergent protein kinase domain 2A isoform c

    Status: VALIDATED

    Source sequence(s)
    AC117379
    Consensus CDS
    CCDS87151.1
    Related
    ENSP00000390796.2, ENST00000441925.2
    Conserved Domains (1) summary
    cl21453
    Location:1167
    PKc_like; Protein Kinases, catalytic domain
  3. NM_173552.5NP_775823.1  divergent protein kinase domain 2A isoform a precursor

    See identical proteins and their annotated locations for NP_775823.1

    Status: VALIDATED

    Source sequence(s)
    AK095400, BC037293, BM968874, DA760601, DB067725
    Consensus CDS
    CCDS3130.1
    UniProtKB/Swiss-Prot
    Q8NDZ4
    UniProtKB/TrEMBL
    B3KTD4
    Related
    ENSP00000320081.3, ENST00000315691.7
    Conserved Domains (1) summary
    cl21453
    Location:206405
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    143971798..143992368
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011512543.2XP_011510845.1  divergent protein kinase domain 2A isoform X1

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