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Slc22a3 solute carrier family 22 (organic cation transporter), member 3 [ Mus musculus (house mouse) ]

Gene ID: 20519, updated on 12-Aug-2018

Summary

Official Symbol
Slc22a3provided by MGI
Official Full Name
solute carrier family 22 (organic cation transporter), member 3provided by MGI
Primary source
MGI:MGI:1333817
See related
Ensembl:ENSMUSG00000023828
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EMT; Oct3; Orct3; Slca22a3
Expression
Biased expression in subcutaneous fat pad adult (RPKM 16.2), genital fat pad adult (RPKM 10.1) and 10 other tissues See more
Orthologs

Genomic context

See Slc22a3 in Genome Data Viewer
Location:
17 A1; 17 8.52 cM
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (12419972..12507704, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (12612838..12700570, complement)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41527 Neighboring gene plasminogen Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 pseudogene Neighboring gene RIKEN cDNA C030013G03 gene Neighboring gene solute carrier family 22 (organic cation transporter), member 2 Neighboring gene solute carrier family 22 (organic cation transporter), member 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
dopamine:sodium symporter activity ISO
Inferred from Sequence Orthology
more info
 
organic cation transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
organic cation transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
PubMed 
quaternary ammonium group transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
quaternary ammonium group transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
toxin transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
dopamine transport ISO
Inferred from Sequence Orthology
more info
 
histamine transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
histamine uptake IMP
Inferred from Mutant Phenotype
more info
PubMed 
ion transport IEA
Inferred from Electronic Annotation
more info
 
monoamine transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
organic cation transport IDA
Inferred from Direct Assay
more info
PubMed 
organic cation transport ISO
Inferred from Sequence Orthology
more info
PubMed 
quaternary ammonium group transport IDA
Inferred from Direct Assay
more info
PubMed 
quaternary ammonium group transport ISO
Inferred from Sequence Orthology
more info
 
regulation of appetite IMP
Inferred from Mutant Phenotype
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier family 22 member 3
Names
organic cation transporter 3
solute carrier family 22, member 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011395.2NP_035525.1  solute carrier family 22 member 3

    See identical proteins and their annotated locations for NP_035525.1

    Status: PROVISIONAL

    Source sequence(s)
    AC087901, AC132106
    Consensus CDS
    CCDS28391.1
    UniProtKB/Swiss-Prot
    Q9WTW5
    UniProtKB/TrEMBL
    Q547K2
    Related
    ENSMUSP00000024595.2, ENSMUST00000024595.2
    Conserved Domains (2) summary
    cd06174
    Location:145513
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:12523
    2A0119; cation transport protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    12419972..12507704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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