U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Slc20a1 solute carrier family 20, member 1 [ Mus musculus (house mouse) ]

Gene ID: 20515, updated on 26-Sep-2022

Summary

Official Symbol
Slc20a1provided by MGI
Official Full Name
solute carrier family 20, member 1provided by MGI
Primary source
MGI:MGI:108392
See related
Ensembl:ENSMUSG00000027397 AllianceGenome:MGI:108392
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Glvr1; Glvr-1
Summary
Predicted to enable high-affinity inorganic phosphate:sodium symporter activity and inorganic phosphate transmembrane transporter activity. Acts upstream of or within biomineral tissue development. Located in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; liver; and nervous system. Orthologous to human SLC20A1 (solute carrier family 20 member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 22.0), frontal lobe adult (RPKM 18.6) and 27 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Slc20a1 in Genome Data Viewer
Location:
2 F1; 2 62.79 cM
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (129038662..129053535)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (129198773..129211615)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene expressed sequence AI847159 Neighboring gene predicted gene, 39932 Neighboring gene RIKEN cDNA A730036I17 gene Neighboring gene cytoskeleton associated protein 2-like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables high-affinity inorganic phosphate:sodium symporter activity ISO
Inferred from Sequence Orthology
more info
 
enables inorganic phosphate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within biomineral tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in phosphate ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in phosphate ion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in sodium ion transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
sodium-dependent phosphate transporter 1
Names
gibbon ape leukemia virus receptor 1
leukemia virus receptor 1 homolog
phosphate transporter 1
piT-1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159593.1NP_001153065.1  sodium-dependent phosphate transporter 1 isoform 2

    See identical proteins and their annotated locations for NP_001153065.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK035898, CD545381
    UniProtKB/Swiss-Prot
    Q61609
    Related
    ENSMUST00000141285.2
    Conserved Domains (2) summary
    COG0306
    Location:25214
    PitA; Phosphate/sulfate permease [Inorganic ion transport and metabolism]
    pfam01384
    Location:46148
    PHO4; Phosphate transporter family
  2. NM_001355252.1NP_001342181.1  sodium-dependent phosphate transporter 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AL772347
    Conserved Domains (1) summary
    pfam01384
    Location:247392
    PHO4; Phosphate transporter family
  3. NM_015747.2NP_056562.1  sodium-dependent phosphate transporter 1 isoform 1

    See identical proteins and their annotated locations for NP_056562.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AI840202, BQ179432, CD545381, M73696
    Consensus CDS
    CCDS16722.1
    UniProtKB/Swiss-Prot
    Q61609, Q9QVW6
    Related
    ENSMUSP00000028880.4, ENSMUST00000028880.10
    Conserved Domains (1) summary
    pfam01384
    Location:509667
    PHO4; Phosphate transporter family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    129038662..129053535
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159901.1XP_036015794.1  sodium-dependent phosphate transporter 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9QVW6
    Conserved Domains (1) summary
    pfam01384
    Location:509667
    PHO4; Phosphate transporter family
  2. XM_011239399.4XP_011237701.1  sodium-dependent phosphate transporter 1 isoform X2

    Conserved Domains (1) summary
    pfam01384
    Location:238410
    PHO4; Phosphate transporter family

RNA

  1. XR_004939188.1 RNA Sequence