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Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 [ Mus musculus (house mouse) ]

Gene ID: 20501, updated on 16-Apr-2019

Summary

Official Symbol
Slc16a1provided by MGI
Official Full Name
solute carrier family 16 (monocarboxylic acid transporters), member 1provided by MGI
Primary source
MGI:MGI:106013
See related
Ensembl:ENSMUSG00000032902
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mct1; AL022710
Expression
Ubiquitous expression in colon adult (RPKM 55.3), placenta adult (RPKM 47.0) and 27 other tissues See more
Orthologs

Genomic context

See Slc16a1 in Genome Data Viewer
Location:
3; 3 F2.2
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (104638664..104658462)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (104442591..104462385)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene leucine-rich repeats and immunoglobulin-like domains 2 Neighboring gene predicted gene, 34490 Neighboring gene predicted gene, 34548 Neighboring gene predicted gene 6485

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
lactate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
monocarboxylic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
organic cyclic compound binding ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
behavioral response to nutrient IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to organic cyclic compound ISO
Inferred from Sequence Orthology
more info
 
centrosome cycle ISO
Inferred from Sequence Orthology
more info
 
glucose homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
lactate transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
lipid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
monocarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane lactate transport ISO
Inferred from Sequence Orthology
more info
 
regulation of insulin secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to food IMP
Inferred from Mutant Phenotype
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell junction ISO
Inferred from Sequence Orthology
more info
 
centrosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion HDA PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
synapse EXP
Inferred from Experiment
more info
PubMed 
synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
monocarboxylate transporter 1
Names
solute carrier family 16 member 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009196.4NP_033222.1  monocarboxylate transporter 1

    See identical proteins and their annotated locations for NP_033222.1

    Status: VALIDATED

    Source sequence(s)
    AK033516, BY729217
    Consensus CDS
    CCDS17702.1
    UniProtKB/Swiss-Prot
    P53986
    UniProtKB/TrEMBL
    Q544N9
    Related
    ENSMUSP00000045216.1, ENSMUST00000046212.1
    Conserved Domains (2) summary
    cd06174
    Location:20432
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00892
    Location:1466
    2A0113; monocarboxylate transporter 1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

    Range
    104638664..104658462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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