U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

St6galnac2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 20446, updated on 18-Apr-2024

Summary

Official Symbol
St6galnac2provided by MGI
Official Full Name
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2provided by MGI
Primary source
MGI:MGI:107553
See related
Ensembl:ENSMUSG00000057286 AllianceGenome:MGI:107553
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
II; Siat7; Siat7b; ST6GalNAc
Summary
Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in protein O-linked glycosylation and protein sialylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; lung; and mammary gland. Orthologous to human ST6GALNAC2 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 210.6), kidney adult (RPKM 42.3) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
11 E2; 11 81.49 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (116567529..116586608, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (116676703..116695782, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA host gene 16 Neighboring gene small nucleolar RNA, C/D box 1B Neighboring gene small nucleolar RNA, C/D box 1A Neighboring gene STARR-seq mESC enhancer starr_31219 Neighboring gene STARR-seq mESC enhancer starr_31222 Neighboring gene predicted gene 11735 Neighboring gene cDNA sequence BC018473

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein O-linked glycosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein glycosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein sialylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Names
Gal-beta-1,3-GalNAc alpha-2,6-sialyltransferase
SIAT7-B
ST6GalNAc II
ST6GalNAcII
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase II
galNAc alpha-2,6-sialyltransferase II
sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-beta-galactosyl-1,3)-N-acetyl galactosaminde alpha-2,6-sialyltransferase) B
sialyltransferase 7B
NP_033206.2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009180.3NP_033206.2  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

    See identical proteins and their annotated locations for NP_033206.2

    Status: PROVISIONAL

    Source sequence(s)
    AK004613
    Consensus CDS
    CCDS36379.1
    UniProtKB/Swiss-Prot
    P70277, Q3UWG0, Q9DC24
    Related
    ENSMUSP00000078501.6, ENSMUST00000079545.6
    Conserved Domains (1) summary
    pfam00777
    Location:110372
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    116567529..116586608 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_388384.4 RNA Sequence