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RTL3 retrotransposon Gag like 3 [ Homo sapiens (human) ]

Gene ID: 203430, updated on 23-Nov-2021

Summary

Official Symbol
RTL3provided by HGNC
Official Full Name
retrotransposon Gag like 3provided by HGNC
Primary source
HGNC:HGNC:22997
See related
Ensembl:ENSG00000179300
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Mar3; ZHC5; Mart3; SIRH9; ZCCHC5
Summary
This gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose; however, their open reading frames have remained intact, which may indicate that these genes have acquired new functions in the cell. [provided by RefSeq, Nov 2009]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See RTL3 in Genome Data Viewer
Location:
Xq21.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (78656068..78659328, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (77911565..77914825, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene high mobility group nucleosome binding domain 1 pseudogene 34 Neighboring gene UBE2V1 pseudogene 7 Neighboring gene uncharacterized LOC107985670 Neighboring gene phosphoribosyl pyrophosphate amidotransferase pseudogene 2 Neighboring gene lysophosphatidic acid receptor 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ38865

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
retrotransposon Gag-like protein 3
Names
Sushi-Ichi retrotransposon homolog 9
mammalian retrotransposon-derived 3
zinc finger CCHC domain-containing protein 5
zinc finger CCHC-type containing 5
zinc finger, CCHC domain containing 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_015973.1 RefSeqGene

    Range
    5001..8261
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_152694.3NP_689907.1  retrotransposon Gag-like protein 3

    See identical proteins and their annotated locations for NP_689907.1

    Status: REVIEWED

    Source sequence(s)
    AI091777, AK096184, AL662885
    Consensus CDS
    CCDS14440.1
    UniProtKB/Swiss-Prot
    Q8N8U3
    Related
    ENSP00000316794.1, ENST00000321110.2
    Conserved Domains (3) summary
    PHA03160
    Location:31161
    PHA03160; hypothetical protein; Provisional
    pfam00098
    Location:443459
    zf-CCHC; Zinc knuckle
    pfam16297
    Location:237316
    DUF4939; Domain of unknown function (DUF4939)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    78656068..78659328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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