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Scd2 stearoyl-Coenzyme A desaturase 2 [ Mus musculus (house mouse) ]

Gene ID: 20250, updated on 31-May-2023


Official Symbol
Scd2provided by MGI
Official Full Name
stearoyl-Coenzyme A desaturase 2provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000025203 AllianceGenome:MGI:98240
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
swty; Scd-2; Mir5114; mir-5114
Enables palmitoyl-CoA 9-desaturase activity and stearoyl-CoA 9-desaturase activity. Acts upstream of or within monounsaturated fatty acid biosynthetic process. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human SCD (stearoyl-CoA desaturase). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in cerebellum adult (RPKM 186.3), subcutaneous fat pad adult (RPKM 170.4) and 25 other tissues See more
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Genomic context

See Scd2 in Genome Data Viewer
19 C3; 19 37.98 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2023_04 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (44282115..44295303)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (44293676..44306864)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54046 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:44358612-44358721 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:44358929-44359038 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:44368225-44368334 Neighboring gene microRNA 5114 Neighboring gene stearoyl-coenzyme A desaturase 4 Neighboring gene stearoyl-Coenzyme A desaturase 1

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


GeneRIFs: Gene References Into Functions

What's a GeneRIF?



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (2) 

Pathways from PubChem


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
located_in membrane ISO
Inferred from Sequence Orthology
more info
located_in nucleolus ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
stearoyl-CoA desaturase 2
Acyl-CoA desaturase 2 (Stearoyl-CoA desaturase 2) (Fatty acid desaturase 2) (Delta(9)-desaturase 2)
delta(9)-desaturase 2
fatty acid desaturase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009128.2NP_033154.2  stearoyl-CoA desaturase 2

    See identical proteins and their annotated locations for NP_033154.2

    Status: VALIDATED

    Source sequence(s)
    AK083922, AK159413, CF168778, CJ110442, CJ242760
    Consensus CDS
    P13011, Q8BH96
    ENSMUSP00000026221.6, ENSMUST00000026221.7
    Conserved Domains (1) summary
    Delta9-FADS-like; The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000085.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)