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Nkx1-2 NK1 homeobox 2 [ Mus musculus (house mouse) ]

Gene ID: 20231, updated on 5-Jun-2018

Summary

Official Symbol
Nkx1-2provided by MGI
Official Full Name
NK1 homeobox 2provided by MGI
Primary source
MGI:MGI:104806
See related
Ensembl:ENSMUSG00000048528 Vega:OTTMUSG00000036708
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sax1; Nkx-1.1; Nkx-1.2
Expression
Biased expression in CNS E11.5 (RPKM 1.3), duodenum adult (RPKM 0.3) and 10 other tissues See more
Orthologs

Genomic context

See Nkx1-2 in Genome Data Viewer
Location:
7; 7 F3
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (132596239..132599637, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (139787922..139791320, complement)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35249 Neighboring gene ornithine aminotransferase Neighboring gene predicted gene, 46021 Neighboring gene phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NK1 transcription factor-related protein 2
Names
NK1 transcription factor related, locus 2
homeobox protein Nkx1.2E427
homeobox protein SAX-1
spinal cord axial homeobox gene 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009123.2NP_033149.1  NK1 transcription factor-related protein 2

    See identical proteins and their annotated locations for NP_033149.1

    Status: PROVISIONAL

    Source sequence(s)
    AF222444
    Consensus CDS
    CCDS21924.1
    UniProtKB/Swiss-Prot
    P42580
    Related
    ENSMUSP00000052778.2, OTTMUSP00000052244, ENSMUST00000054562.3, OTTMUST00000094047
    Conserved Domains (1) summary
    pfam00046
    Location:160212
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

    Range
    132596239..132599637 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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