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SPATA24 spermatogenesis associated 24 [ Homo sapiens (human) ]

Gene ID: 202051, updated on 25-Jan-2022

Summary

Official Symbol
SPATA24provided by HGNC
Official Full Name
spermatogenesis associated 24provided by HGNC
Primary source
HGNC:HGNC:27322
See related
Ensembl:ENSG00000170469 AllianceGenome:HGNC:27322
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T6441; CCDC161
Summary
Predicted to enable DNA binding activity and identical protein binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in testis (RPKM 10.5), prostate (RPKM 2.2) and 14 other tissues See more
Orthologs
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Genomic context

See SPATA24 in Genome Data Viewer
Location:
5q31.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (139395269..139404204, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (138732456..138739778, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 996 Neighboring gene marginal zone B and B1 cell specific protein Neighboring gene proline rich basic protein 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C18 Neighboring gene RNA, U5B small nuclear 4, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
spermatogenesis-associated protein 24
Names
coiled-coil domain containing 161
testis protein T6441 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_194296.2NP_919272.1  spermatogenesis-associated protein 24

    See identical proteins and their annotated locations for NP_919272.1

    Status: VALIDATED

    Source sequence(s)
    AA399058, AC135457, BC040037, BM785501
    Consensus CDS
    CCDS47274.1
    UniProtKB/Swiss-Prot
    Q86W54
    Related
    ENSP00000414920.2, ENST00000450845.7
    Conserved Domains (1) summary
    pfam15175
    Location:25191
    SPATA24; Spermatogenesis-associated protein 24

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    139395269..139404204 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005271916.4XP_005271973.1  spermatogenesis-associated protein 24 isoform X1

    Conserved Domains (3) summary
    pfam13863
    Location:50161
    DUF4200; Domain of unknown function (DUF4200)
    pfam15175
    Location:25162
    SPATA24; Spermatogenesis-associated protein 24
    pfam16006
    Location:130220
    NUSAP; Nucleolar and spindle-associated protein
  2. XM_011543252.2XP_011541554.1  spermatogenesis-associated protein 24 isoform X2

    See identical proteins and their annotated locations for XP_011541554.1

    Conserved Domains (3) summary
    pfam13863
    Location:11122
    DUF4200; Domain of unknown function (DUF4200)
    pfam15175
    Location:1123
    SPATA24; Spermatogenesis-associated protein 24
    pfam16006
    Location:91181
    NUSAP; Nucleolar and spindle-associated protein
  3. XM_011543253.2XP_011541555.1  spermatogenesis-associated protein 24 isoform X2

    See identical proteins and their annotated locations for XP_011541555.1

    Conserved Domains (3) summary
    pfam13863
    Location:11122
    DUF4200; Domain of unknown function (DUF4200)
    pfam15175
    Location:1123
    SPATA24; Spermatogenesis-associated protein 24
    pfam16006
    Location:91181
    NUSAP; Nucleolar and spindle-associated protein
  4. XM_011543254.2XP_011541556.1  spermatogenesis-associated protein 24 isoform X3

    Conserved Domains (1) summary
    pfam15175
    Location:25134
    SPATA24; Spermatogenesis-associated protein 24
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