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RWDD4 RWD domain containing 4 [ Homo sapiens (human) ]

Gene ID: 201965, updated on 26-Sep-2020

Summary

Official Symbol
RWDD4provided by HGNC
Official Full Name
RWD domain containing 4provided by HGNC
Primary source
HGNC:HGNC:23750
See related
Ensembl:ENSG00000182552
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM28A; RWDD4A
Expression
Ubiquitous expression in adrenal (RPKM 29.0), ovary (RPKM 20.4) and 25 other tissues See more
Orthologs

Genomic context

See RWDD4 in Genome Data Viewer
Location:
4q35.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (183639635..183659218, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (184560789..184580331, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377579 Neighboring gene uncharacterized LOC105377580 Neighboring gene uncharacterized LOC107986329 Neighboring gene RNA, U6 small nuclear 479, pseudogene Neighboring gene trafficking protein particle complex 11 Neighboring gene RNA, U6 small nuclear 335, pseudogene Neighboring gene RNA, U6 small nuclear 1053, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC10198

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
RWD domain-containing protein 4
Names
RWD domain containing 4A
RWD domain-containing protein 4A
family with sequence similarity 28, member A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001307922.2NP_001294851.1  RWD domain-containing protein 4 isoform 2

    See identical proteins and their annotated locations for NP_001294851.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate splice site in the 5' coding region, which results in use of a downstream start codon compared to variant 1. It encodes isoform 2, which has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC108477, AK315515, AL540937, AL559547, BC017472, BQ185399, DA250301, DA766837
    Consensus CDS
    CCDS77986.1
    UniProtKB/Swiss-Prot
    Q6NW29
    UniProtKB/TrEMBL
    E7EV43
    Related
    ENSP00000423598.1, ENST00000512740.1
    Conserved Domains (1) summary
    cl02687
    Location:644
    RWD; RWD domain
  2. NM_152682.4NP_689895.2  RWD domain-containing protein 4 isoform 1

    See identical proteins and their annotated locations for NP_689895.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC108477, AK315515, AL540937, BC017472, BQ185399, DA250301, DA766837
    Consensus CDS
    CCDS34111.1
    UniProtKB/Swiss-Prot
    Q6NW29
    Related
    ENSP00000388920.2, ENST00000326397.10
    Conserved Domains (1) summary
    pfam05773
    Location:5107
    RWD; RWD domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    183639635..183659218 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_002959716.1 RNA Sequence

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