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Ryr1 ryanodine receptor 1, skeletal muscle [ Mus musculus (house mouse) ]

Gene ID: 20190, updated on 9-Mar-2023

Summary

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Official Symbol
Ryr1provided by MGI
Official Full Name
ryanodine receptor 1, skeletal muscleprovided by MGI
Primary source
MGI:MGI:99659
See related
Ensembl:ENSMUSG00000030592 AllianceGenome:MGI:99659
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ryr; skrr; RYR-1
Summary
Enables protease binding activity; ryanodine-sensitive calcium-release channel activity; and voltage-gated calcium channel activity. Involved in animal organ development; cellular response to caffeine; and release of sequestered calcium ion into cytosol by sarcoplasmic reticulum. Acts upstream of or within muscle contraction and release of sequestered calcium ion into cytosol. Located in T-tubule; sarcoplasmic reticulum membrane; and smooth endoplasmic reticulum. Part of junctional membrane complex. Is expressed in several structures, including brain; embryo mesenchyme; endocrine gland; heart; and skeletal musculature. Used to study central core disease and malignant hyperthermia. Human ortholog(s) of this gene implicated in central core disease; malignant hyperthermia; and multiminicore disease. Orthologous to human RYR1 (ryanodine receptor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in mammary gland adult (RPKM 14.4), limb E14.5 (RPKM 5.1) and 8 other tissues See more
Orthologs
human all
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Genomic context

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See Ryr1 in Genome Data Viewer
Location:
7 B1; 7 16.94 cM
Exon count:
108
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28702765..28824599, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29003340..29125179, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3, subunit K Neighboring gene mitogen-activated protein kinase kinase kinase kinase 1 Neighboring gene predicted gene, 38979 Neighboring gene predicted gene, 26604 Neighboring gene microRNA 1963 Neighboring gene RAS guanyl releasing protein 4 Neighboring gene family with sequence similarity 98, member C Neighboring gene sprouty-related EVH1 domain containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mice with R2509C-RYR1 mutation exhibit dysfunctional Ca2+ dynamics in primary skeletal myocytes. Tsuboi Y, et al. J Gen Physiol, 2022 Nov 7. PMID 36200983,
  2. Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors. Ruiz A, et al. Elife, 2022 Mar 3. PMID 35238775, Free PMC Article
  3. Ca(2+) leak through ryanodine receptor 1 regulates thermogenesis in resting skeletal muscle. Meizoso-Huesca A, et al. Proc Natl Acad Sci U S A, 2022 Jan 25. PMID 35046046, Free PMC Article
  4. A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke. Yamazawa T, et al. Nat Commun, 2021 Jul 13. PMID 34257294, Free PMC Article
  5. In vivo RyR1 reduction in muscle triggers a core-like myopathy. Pelletier L, et al. Acta Neuropathol Commun, 2020 Nov 11. PMID 33176865, Free PMC Article

See all (257) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mice with R2509C-RYR1 mutation exhibit dysfunctional Ca2+ dynamics in primary skeletal myocytes.
    Title: Mice with R2509C-RYR1 mutation exhibit dysfunctional Ca2+ dynamics in primary skeletal myocytes.
  2. Ca(2+) leak through ryanodine receptor 1 regulates thermogenesis in resting skeletal muscle.
    Title: Ca(2+) leak through ryanodine receptor 1 regulates thermogenesis in resting skeletal muscle.
  3. Acute RyR1 Ca(2+) leak enhances NADH-linked mitochondrial respiratory capacity.
    Title: Acute RyR1 Ca(2+) leak enhances NADH-linked mitochondrial respiratory capacity.
  4. In vivo RyR1 reduction in muscle triggers a core-like myopathy.
    Title: In vivo RyR1 reduction in muscle triggers a core-like myopathy.
  5. Neuron-derived factors negatively modulate ryanodine receptor-mediated calcium release in cultured mouse astrocytes.
    Title: Neuron-derived factors negatively modulate ryanodine receptor-mediated calcium release in cultured mouse astrocytes.
  6. Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle.
    Title: Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle.
  7. Molecular basis of impaired extraocular muscle function in a mouse model of congenital myopathy due to compound heterozygous Ryr1 mutations.
    Title: Molecular basis of impaired extraocular muscle function in a mouse model of congenital myopathy due to compound heterozygous Ryr1 mutations.
  8. iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin.
    Title: iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin.
  9. Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia.
    Title: Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia.
  10. Bi-allelic expression of the RyR1 p.A4329D mutation decreases muscle strength in slow-twitch muscles in mice.
    Title: Bi-allelic expression of the RyR1 p.A4329D mutation decreases muscle strength in slow-twitch muscles in mice.
Submit: New GeneRIF Correction See all GeneRIFs (110)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-induced calcium release activity IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables calcium-induced calcium release activity ISO
Inferred from Sequence Orthology
more info
  
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables enzyme binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protease binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ryanodine-sensitive calcium-release channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables ryanodine-sensitive calcium-release channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables ryanodine-sensitive calcium-release channel activity ISO
Inferred from Sequence Orthology
more info
  
enables voltage-gated calcium channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within calcium ion transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in calcium ion transport ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular response to ATP ISO
Inferred from Sequence Orthology
more info
  
involved_in cellular response to caffeine IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to caffeine ISO
Inferred from Sequence Orthology
more info
  
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within muscle contraction IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within muscle contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in muscle contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ossification involved in bone maturation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in outflow tract morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of muscle contraction TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within release of sequestered calcium ion into cytosol IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
  
involved_in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
involved_in response to caffeine ISO
Inferred from Sequence Orthology
more info
  
involved_in response to hypoxia ISO
Inferred from Sequence Orthology
more info
  
involved_in sarcoplasmic reticulum calcium ion transport ISO
Inferred from Sequence Orthology
more info
  
involved_in skeletal muscle fiber development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in skin development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in striated muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in I band ISO
Inferred from Sequence Orthology
more info
  
located_in T-tubule IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in Z disc IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
part_of calcium channel complex IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in extrinsic component of cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
  
part_of junctional membrane complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in sarcolemma IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in sarcolemma ISO
Inferred from Sequence Orthology
more info
  
located_in sarcoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in sarcoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
is_active_in sarcoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in sarcoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in sarcoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
is_active_in smooth endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in smooth endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in terminal cisterna ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ryanodine receptor 1
Names
calcium release channel
skeletal muscle calcium release channel
skeletal muscle ryanodine receptor
skeletal muscle-type ryanodine receptor
type 1 ryanodine receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009109.2 → NP_033135.2  ryanodine receptor 1

    See identical proteins and their annotated locations for NP_033135.2

    Status: VALIDATED

    Source sequence(s)
    AC164564, AC165142
    Consensus CDS
    CCDS39866.1
    UniProtKB/Swiss-Prot
    E9PZQ0, Q99JF9
    Related
    ENSMUSP00000137123.2, ENSMUST00000179893.9
    Conserved Domains (12) summary
    smart00472
    Location:212 → 265
    MIR; Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
    cd12877
    Location:644 → 795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1074 → 1206
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    pfam00520
    Location:4762 → 4946
    Ion_trans; Ion transport protein
    pfam01365
    Location:445 → 633
    RYDR_ITPR; RIH domain
    pfam02026
    Location:852 → 942
    RyR; RyR domain
    pfam02815
    Location:213 → 391
    MIR; MIR domain
    pfam06459
    Location:4380 → 4668
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:3883 → 3996
    RIH_assoc; RyR and IP3R Homology associated
    pfam13833
    Location:4087 → 4137
    EF-hand_8; EF-hand domain pair
    cd12879
    Location:1420 → 1568
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    cl19745
    Location:12 → 205
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    28702765..28824599 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152819.1 → XP_036008712.1  ryanodine receptor 1 isoform X7

    Conserved Domains (10) summary
    cd12877
    Location:644 → 795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1074 → 1206
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:1420 → 1568
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:4751 → 4935
    Ion_trans; Ion transport protein
    pfam01365
    Location:445 → 638
    RYDR_ITPR; RIH domain
    pfam02026
    Location:852 → 942
    RyR; RyR domain
    pfam02815
    Location:213 → 391
    MIR; MIR domain
    pfam06459
    Location:4369 → 4657
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:3869 → 3985
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:12 → 211
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  2. XM_036152817.1 → XP_036008710.1  ryanodine receptor 1 isoform X4

    Conserved Domains (10) summary
    cd12877
    Location:644 → 795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1074 → 1206
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:1420 → 1568
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:4770 → 4954
    Ion_trans; Ion transport protein
    pfam01365
    Location:445 → 638
    RYDR_ITPR; RIH domain
    pfam02026
    Location:852 → 942
    RyR; RyR domain
    pfam02815
    Location:213 → 391
    MIR; MIR domain
    pfam06459
    Location:4388 → 4676
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:3869 → 3985
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:12 → 211
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  3. XM_006539689.4 → XP_006539752.1  ryanodine receptor 1 isoform X5

    Related
    ENSMUSP00000032813.10, ENSMUST00000032813.10
    Conserved Domains (11) summary
    cd12877
    Location:644 → 795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1074 → 1206
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:1420 → 1568
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:4757 → 4941
    Ion_trans; Ion transport protein
    pfam01365
    Location:443 → 638
    RYDR_ITPR; RIH domain
    pfam02026
    Location:852 → 942
    RyR; RyR domain
    pfam02815
    Location:213 → 391
    MIR; MIR domain
    pfam06459
    Location:4375 → 4663
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:3878 → 3991
    RIH_assoc; RyR and IP3R Homology associated
    pfam13833
    Location:4082 → 4132
    EF-hand_8; EF-hand domain pair
    cl19745
    Location:12 → 205
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  4. XM_036152815.1 → XP_036008708.1  ryanodine receptor 1 isoform X2

    Conserved Domains (10) summary
    cd12877
    Location:644 → 795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1074 → 1206
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:1420 → 1568
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:4776 → 4960
    Ion_trans; Ion transport protein
    pfam01365
    Location:445 → 638
    RYDR_ITPR; RIH domain
    pfam02026
    Location:852 → 942
    RyR; RyR domain
    pfam02815
    Location:213 → 391
    MIR; MIR domain
    pfam06459
    Location:4394 → 4682
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:3875 → 3991
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:12 → 211
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  5. XM_036152818.1 → XP_036008711.1  ryanodine receptor 1 isoform X6

    Conserved Domains (10) summary
    cd12877
    Location:644 → 795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1074 → 1206
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:1420 → 1568
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:4756 → 4940
    Ion_trans; Ion transport protein
    pfam01365
    Location:445 → 638
    RYDR_ITPR; RIH domain
    pfam02026
    Location:852 → 942
    RyR; RyR domain
    pfam02815
    Location:213 → 391
    MIR; MIR domain
    pfam06459
    Location:4374 → 4662
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:3874 → 3990
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:12 → 211
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  6. XM_036152816.1 → XP_036008709.1  ryanodine receptor 1 isoform X3

    Conserved Domains (10) summary
    cd12877
    Location:644 → 795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1074 → 1206
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:1420 → 1568
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:4775 → 4959
    Ion_trans; Ion transport protein
    pfam01365
    Location:445 → 638
    RYDR_ITPR; RIH domain
    pfam02026
    Location:852 → 942
    RyR; RyR domain
    pfam02815
    Location:213 → 391
    MIR; MIR domain
    pfam06459
    Location:4393 → 4681
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:3874 → 3990
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:12 → 211
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  7. XM_036152814.1 → XP_036008707.1  ryanodine receptor 1 isoform X1

    Related
    ENSMUSP00000149042.2, ENSMUST00000214374.2
    Conserved Domains (10) summary
    cd12877
    Location:644 → 795
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1074 → 1206
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:1420 → 1568
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:4781 → 4965
    Ion_trans; Ion transport protein
    pfam01365
    Location:445 → 638
    RYDR_ITPR; RIH domain
    pfam02026
    Location:852 → 942
    RyR; RyR domain
    pfam02815
    Location:213 → 391
    MIR; MIR domain
    pfam06459
    Location:4399 → 4687
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:3880 → 3996
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:12 → 211
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E9PZQ0.1 GenPept UniProtKB/Swiss-Prot:E9PZQ0

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