Format

Send to:

Choose Destination

SAMD14 sterile alpha motif domain containing 14 [ Homo sapiens (human) ]

Gene ID: 201191, updated on 23-Nov-2021

Summary

Official Symbol
SAMD14provided by HGNC
Official Full Name
sterile alpha motif domain containing 14provided by HGNC
Primary source
HGNC:HGNC:27312
See related
Ensembl:ENSG00000167100 MIM:619233
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in ovary (RPKM 5.2), adrenal (RPKM 5.0) and 24 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SAMD14 in Genome Data Viewer
Location:
17q21.33
Exon count:
14
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (50110040..50130160, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (48187404..48207524, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene p53 inducible cancer associated RNA transcript 1 Neighboring gene integrin subunit alpha 3 Neighboring gene pyruvate dehydrogenase kinase 2 Neighboring gene protein phosphatase 1 regulatory subunit 9B Neighboring gene Sharpr-MPRA regulatory region 5931

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Clone Names

  • FLJ30281, FLJ36890

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in calcium-mediated signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
sterile alpha motif domain-containing protein 14
Names
SAM domain-containing protein 14

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257359.2NP_001244288.1  sterile alpha motif domain-containing protein 14 isoform 2

    See identical proteins and their annotated locations for NP_001244288.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC002401, AF035306, AK094209, BM973393, CN369613
    Consensus CDS
    CCDS58562.1
    UniProtKB/Swiss-Prot
    Q8IZD0
    Related
    ENSP00000329144.4, ENST00000330175.9
    Conserved Domains (2) summary
    cd09512
    Location:321386
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
    smart00454
    Location:323386
    SAM; Sterile alpha motif
  2. NM_174920.4NP_777580.1  sterile alpha motif domain-containing protein 14 isoform 1

    See identical proteins and their annotated locations for NP_777580.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC002401, AF035306, AY148482, BM973393, CN369613
    Consensus CDS
    CCDS11560.1
    UniProtKB/Swiss-Prot
    Q8IZD0
    Related
    ENSP00000424474.1, ENST00000503131.1
    Conserved Domains (2) summary
    cd09512
    Location:349414
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
    smart00454
    Location:351414
    SAM; Sterile alpha motif

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    50110040..50130160 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024323.2XP_016879812.1  sterile alpha motif domain-containing protein 14 isoform X2

    UniProtKB/Swiss-Prot
    Q8IZD0
    Conserved Domains (2) summary
    cd09512
    Location:321386
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
    smart00454
    Location:323386
    SAM; Sterile alpha motif
  2. XM_017024324.2XP_016879813.1  sterile alpha motif domain-containing protein 14 isoform X4

    UniProtKB/Swiss-Prot
    Q8IZD0
    Conserved Domains (2) summary
    cd09512
    Location:349414
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
    smart00454
    Location:351414
    SAM; Sterile alpha motif
  3. XM_017024322.2XP_016879811.1  sterile alpha motif domain-containing protein 14 isoform X1

    Related
    ENSP00000285206.8, ENST00000285206.12
  4. XM_011524490.3XP_011522792.1  sterile alpha motif domain-containing protein 14 isoform X3

    See identical proteins and their annotated locations for XP_011522792.1

    UniProtKB/TrEMBL
    B3KTM3
    Related
    ENST00000508892.5
    Conserved Domains (2) summary
    cd09512
    Location:104169
    SAM_Neurabin-like; SAM domain of SAM_Neurabin-like subfamily
    smart00454
    Location:106169
    SAM; Sterile alpha motif
Support Center