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RPL22L1 ribosomal protein L22 like 1 [ Homo sapiens (human) ]

Gene ID: 200916, updated on 7-Jun-2020

Summary

Official Symbol
RPL22L1provided by HGNC
Official Full Name
ribosomal protein L22 like 1provided by HGNC
Primary source
HGNC:HGNC:27610
See related
Ensembl:ENSG00000163584
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in bone marrow (RPKM 15.2), appendix (RPKM 13.6) and 25 other tissues See more
Orthologs

Genomic context

See RPL22L1 in Genome Data Viewer
Location:
3q26.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (170864875..170870195, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (170582664..170588045, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374211 Neighboring gene RNY5 pseudogene 3 Neighboring gene eukaryotic translation initiation factor 5A2 Neighboring gene kruppel like factor 7 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC104449

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
60S ribosomal protein L22-like 1
Names
large ribosomal subunit protein eL22-like 1
NP_001093115.1
NP_001307380.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099645.2NP_001093115.1  60S ribosomal protein L22-like 1 isoform 1

    See identical proteins and their annotated locations for NP_001093115.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1),
    Source sequence(s)
    AC061708, BC062731, CA449264
    Consensus CDS
    CCDS46955.1
    UniProtKB/Swiss-Prot
    Q6P5R6
    Related
    ENSP00000346080.7, ENST00000295830.13
    Conserved Domains (1) summary
    pfam01776
    Location:12117
    Ribosomal_L22e; Ribosomal L22e protein family
  2. NM_001320451.2NP_001307380.1  60S ribosomal protein L22-like 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC061708, BU540139, CA449264
    Consensus CDS
    CCDS82875.1
    UniProtKB/TrEMBL
    C9JYQ9
    Related
    ENSP00000419041.1, ENST00000463836.1
    Conserved Domains (1) summary
    pfam01776
    Location:11116
    Ribosomal_L22e; Ribosomal L22e protein family

RNA

  1. NR_135259.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site, in an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5' most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC061708, AL110170, BM451642, CA449264

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    170864875..170870195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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