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TIGD1 tigger transposable element derived 1 [ Homo sapiens (human) ]

Gene ID: 200765, updated on 1-Jun-2020

Summary

Official Symbol
TIGD1provided by HGNC
Official Full Name
tigger transposable element derived 1provided by HGNC
Primary source
HGNC:HGNC:14523
See related
Ensembl:ENSG00000221944 MIM:612972
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EEYORE
Summary
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See TIGD1 in Genome Data Viewer
Location:
2q37.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (232543883..232550557, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (233412779..233415226, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene serine protease 56 Neighboring gene cholinergic receptor nicotinic delta subunit Neighboring gene cholinergic receptor nicotinic gamma subunit Neighboring gene microRNA 5001 Neighboring gene eukaryotic translation initiation factor 4E family member 2 Neighboring gene uncharacterized LOC105373929 Neighboring gene EF-hand domain family member D1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
tigger transposable element-derived protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145702.4NP_663748.1  tigger transposable element-derived protein 1

    See identical proteins and their annotated locations for NP_663748.1

    Status: VALIDATED

    Source sequence(s)
    AC092165
    Consensus CDS
    CCDS2495.1
    UniProtKB/Swiss-Prot
    Q96MW7
    Related
    ENSP00000386186.3, ENST00000408957.6
    Conserved Domains (3) summary
    smart00674
    Location:76149
    CENPB; Putative DNA-binding domain in centromere protein B, mouse jerky and transposases
    pfam03184
    Location:216403
    DDE_1; DDE superfamily endonuclease
    pfam04218
    Location:960
    CENP-B_N; CENP-B N-terminal DNA-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    232543883..232550557 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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