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FOXD4L1 forkhead box D4 like 1 [ Homo sapiens (human) ]

Gene ID: 200350, updated on 13-Mar-2020

Summary

Official Symbol
FOXD4L1provided by HGNC
Official Full Name
forkhead box D4 like 1provided by HGNC
Primary source
HGNC:HGNC:18521
See related
Ensembl:ENSG00000184492 MIM:611084
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FOXD5; bA395L14.1
Summary
This gene is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains. Members of the FOX family of transcription factors are regulators of embryogenesis and may play a role in human cancer. This gene lies in a region of chromosome 2 that surrounds the site where two ancestral chromosomes fused to form human chromosome 2. This region is duplicated elsewhere in the human genome, primarily in subtelomeric and pericentromeric locations, thus mutiple copies of this gene have been found. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See FOXD4L1 in Genome Data Viewer
Location:
2q14.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (113499084..113501150)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (114256661..114258727)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101927400 Neighboring gene uncharacterized LOC107985936 Neighboring gene COBW domain containing 2 Neighboring gene uncharacterized LOC112268422 Neighboring gene long intergenic non-protein coding RNA 1961 Neighboring gene PGM5P4 antisense RNA 1 Neighboring gene phosphoglucomutase 5 pseudogene 4

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
forkhead box protein D4-like 1
Names
FOXD4-like 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012184.4NP_036316.1  forkhead box protein D4-like 1

    See identical proteins and their annotated locations for NP_036316.1

    Status: REVIEWED

    Source sequence(s)
    AK122950, AK125398, AY344639
    Consensus CDS
    CCDS2117.1
    UniProtKB/Swiss-Prot
    Q9NU39
    UniProtKB/TrEMBL
    B3KVK3
    Related
    ENSP00000302756.5, ENST00000306507.6
    Conserved Domains (1) summary
    pfam00250
    Location:107193
    Forkhead; Forkhead domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    113499084..113501150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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