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RNF215 ring finger protein 215 [ Homo sapiens (human) ]

Gene ID: 200312, updated on 11-Jun-2021

Summary

Official Symbol
RNF215provided by HGNC
Official Full Name
ring finger protein 215provided by HGNC
Primary source
HGNC:HGNC:33434
See related
Ensembl:ENSG00000099999
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in brain (RPKM 6.2), endometrium (RPKM 5.2) and 25 other tissues See more
Orthologs
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Genomic context

See RNF215 in Genome Data Viewer
Location:
22q12.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (30378821..30387411, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (30774810..30783400, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene splicing factor 3a subunit 1 Neighboring gene coiled-coil domain containing 157 Neighboring gene KIAA1656 protein Neighboring gene SEC14 like lipid binding 2 Neighboring gene uncharacterized LOC105372989 Neighboring gene RNA, U6 small nuclear 564, pseudogene Neighboring gene mitochondrial fission process 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in Golgi to vacuole transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein targeting to vacuole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of Golgi transport complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017981.2NP_001017981.1  RING finger protein 215 precursor

    See identical proteins and their annotated locations for NP_001017981.1

    Status: VALIDATED

    Source sequence(s)
    AC004997, BM476400, BM806918, BX494669
    Consensus CDS
    CCDS33633.1
    UniProtKB/Swiss-Prot
    Q9Y6U7
    Related
    ENSP00000371800.3, ENST00000382363.8
    Conserved Domains (1) summary
    pfam13639
    Location:323366
    zf-RING_2; Ring finger domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    30378821..30387411 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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