Format

Send to:

Choose Destination

SLFNL1 schlafen like 1 [ Homo sapiens (human) ]

Gene ID: 200172, updated on 11-Sep-2019

Summary

Official Symbol
SLFNL1provided by HGNC
Official Full Name
schlafen like 1provided by HGNC
Primary source
HGNC:HGNC:26313
See related
Ensembl:ENSG00000171790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 12.5) and lung (RPKM 0.6) See more
Orthologs

Genomic context

See SLFNL1 in Genome Data Viewer
Location:
1p34.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (41015597..41024704, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (41481269..41489116, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ubiquitin conjugating enzyme E2 V1 pseudogene 8 Neighboring gene CTP synthase 1 Neighboring gene SLFNL1 antisense RNA 1 Neighboring gene Scm polycomb group protein homolog 1 Neighboring gene ribosomal protein L23a pseudogene 17 Neighboring gene ribosomal protein L36a pseudogene 9

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23878, MGC43873

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
schlafen-like protein 1
Names
testicular tissue protein Li 173

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168247.2NP_001161719.1  schlafen-like protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001161719.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses two alternate splice sites in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AK292296, AL391730, BC022037, DB046748
    Consensus CDS
    CCDS460.1
    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Related
    ENSP00000398938.2, ENST00000439569.2
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  2. NM_001300859.2NP_001287788.1  schlafen-like protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001287788.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site in the 5' UTR and an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AK097609, BC022037
    Consensus CDS
    CCDS72766.1
    UniProtKB/Swiss-Prot
    Q499Z3
    Related
    ENSP00000361694.1, ENST00000372611.5
    Conserved Domains (1) summary
    pfam04326
    Location:162294
    AlbA_2; Putative DNA-binding domain
  3. NM_144990.4NP_659427.3  schlafen-like protein 1 isoform 1

    See identical proteins and their annotated locations for NP_659427.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AL391730, BC022037, DB046748
    Consensus CDS
    CCDS460.1
    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    41015597..41024704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011540953.3XP_011539255.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539255.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  2. XM_006710432.4XP_006710495.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006710495.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  3. XM_011540952.2XP_011539254.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539254.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  4. XM_011540949.2XP_011539251.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539251.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  5. XM_011540945.2XP_011539247.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539247.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Related
    ENSP00000352299.1, ENST00000359345.5
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  6. XM_011540948.2XP_011539250.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539250.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  7. XM_024453869.1XP_024309637.1  schlafen-like protein 1 isoform X3

    Conserved Domains (1) summary
    pfam04326
    Location:161293
    AlbA_2; Putative DNA-binding domain
  8. XM_024453868.1XP_024309636.1  schlafen-like protein 1 isoform X2

    Related
    ENSP00000361696.2, ENST00000372613.6
    Conserved Domains (1) summary
    pfam04326
    Location:221305
    AlbA_2; Putative DNA-binding domain
  9. XM_005270599.2XP_005270656.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005270656.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  10. XM_005270598.2XP_005270655.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005270655.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Related
    ENSP00000304401.8, ENST00000302946.12
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  11. XM_011540947.1XP_011539249.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539249.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
  12. XM_011540951.1XP_011539253.1  schlafen-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011539253.1

    UniProtKB/Swiss-Prot
    Q499Z3
    UniProtKB/TrEMBL
    A0A140VJU6
    Conserved Domains (1) summary
    pfam04326
    Location:221353
    AlbA_2; Putative DNA-binding domain
Support Center