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DYNLT5 dynein light chain Tctex-type family member 5 [ Homo sapiens (human) ]

Gene ID: 200132, updated on 23-Nov-2021

Summary

Official Symbol
DYNLT5provided by HGNC
Official Full Name
dynein light chain Tctex-type family member 5provided by HGNC
Primary source
HGNC:HGNC:26882
See related
Ensembl:ENSG00000152760
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TCTEX1D1
Expression
Broad expression in placenta (RPKM 2.7), liver (RPKM 2.4) and 14 other tissues See more
Orthologs
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Genomic context

See DYNLT5 in Genome Data Viewer
Location:
1p31.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (66752147..66779051)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (67218142..67244730)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378776 Neighboring gene SH3GL interacting endocytic adaptor 1 Neighboring gene microRNA 3117 Neighboring gene insulin like 5 Neighboring gene dynein axonemal intermediate chain 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ40873, MGC125768

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables dynein intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of cytoplasmic dynein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
dynein light chain Tctex-type 5
Names
Tctex1 domain containing 1
tctex1 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152665.3NP_689878.2  dynein light chain Tctex-type 5

    See identical proteins and their annotated locations for NP_689878.2

    Status: VALIDATED

    Source sequence(s)
    AI016360, AK098192, AL354978
    Consensus CDS
    CCDS633.1
    UniProtKB/Swiss-Prot
    Q8N7M0
    Related
    ENSP00000282670.2, ENST00000282670.7
    Conserved Domains (1) summary
    pfam03645
    Location:81177
    Tctex-1; Tctex-1 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    66752147..66779051
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011540933.2XP_011539235.1  dynein light chain Tctex-type 5 isoform X2

    Conserved Domains (1) summary
    pfam03645
    Location:64160
    Tctex-1; Tctex-1 family
  2. XM_017000566.1XP_016856055.1  dynein light chain Tctex-type 5 isoform X1

    UniProtKB/Swiss-Prot
    Q8N7M0
    Conserved Domains (1) summary
    pfam03645
    Location:81177
    Tctex-1; Tctex-1 family
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