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TMEM61 transmembrane protein 61 [ Homo sapiens (human) ]

Gene ID: 199964, updated on 22-Sep-2022

Summary

Official Symbol
TMEM61provided by HGNC
Official Full Name
transmembrane protein 61provided by HGNC
Primary source
HGNC:HGNC:27296
See related
Ensembl:ENSG00000143001 AllianceGenome:HGNC:27296
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney (RPKM 2.5), salivary gland (RPKM 2.4) and 12 other tissues See more
Orthologs
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Genomic context

See TMEM61 in Genome Data Viewer
Location:
1p32.3
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (54980628..54992288)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (54860862..54872524)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (55446301..55457961)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904184 Neighboring gene tRNA-Lys (anticodon CTT) 7-1 Neighboring gene uncharacterized LOC105378736 Neighboring gene barttin CLCNK type accessory subunit beta Neighboring gene proprotein convertase subtilisin/kexin type 9

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_182532.3NP_872338.1  transmembrane protein 61

    See identical proteins and their annotated locations for NP_872338.1

    Status: VALIDATED

    Source sequence(s)
    AA918832, AL590440, BC029775, BG430102
    Consensus CDS
    CCDS601.1
    UniProtKB/Swiss-Prot
    Q8N0U2
    Related
    ENSP00000360315.3, ENST00000371268.4
    Conserved Domains (1) summary
    pfam15105
    Location:13206
    TMEM61; TMEM61 protein family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    54980628..54992288
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011540911.3XP_011539213.1  transmembrane protein 61 isoform X1

    See identical proteins and their annotated locations for XP_011539213.1

    UniProtKB/Swiss-Prot
    Q8N0U2
    Conserved Domains (1) summary
    pfam15105
    Location:13206
    TMEM61; TMEM61 protein family
  2. XM_005270586.5XP_005270643.1  transmembrane protein 61 isoform X2

    See identical proteins and their annotated locations for XP_005270643.1

    Conserved Domains (1) summary
    pfam15105
    Location:8201
    TMEM61; TMEM61 protein family
  3. XM_011540912.3XP_011539214.1  transmembrane protein 61 isoform X2

    See identical proteins and their annotated locations for XP_011539214.1

    Conserved Domains (1) summary
    pfam15105
    Location:8201
    TMEM61; TMEM61 protein family

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    54860862..54872524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)