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ADM5 adrenomedullin 5 (putative) [ Homo sapiens (human) ]

Gene ID: 199800, updated on 5-Jan-2022

Summary

Official Symbol
ADM5provided by HGNC
Official Full Name
adrenomedullin 5 (putative)provided by HGNC
Primary source
HGNC:HGNC:27293
See related
Ensembl:ENSG00000224420
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AM5; C19orf76
Summary
Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; positive regulation of heart rate; and regulation of urine volume. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See ADM5 in Genome Data Viewer
Location:
19q13.33
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (49689594..49690575)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (50192851..50193832)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene interferon regulatory factor 3 Neighboring gene BCL2 like 12 Neighboring gene protein arginine methyltransferase 1 Neighboring gene microRNA 5088 Neighboring gene carnitine palmitoyltransferase 1C Neighboring gene CRISPRi-validated cis-regulatory element chr19.5489

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables adrenomedullin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in adrenomedullin receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in biological_process ND
No biological Data available
more info
 
involved_in positive regulation of heart rate IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of systemic arterial blood pressure IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
putative adrenomedullin-5-like protein
Names
adrenomedullin 5 homolog (pig)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101340.2NP_001094810.1  putative adrenomedullin-5-like protein precursor

    See identical proteins and their annotated locations for NP_001094810.1

    Status: VALIDATED

    Source sequence(s)
    AC011495
    Consensus CDS
    CCDS46146.1
    UniProtKB/Swiss-Prot
    C9JUS6
    Related
    ENSP00000393631.2, ENST00000420022.4

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    49689594..49690575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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