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Rpl27 ribosomal protein L27 [ Mus musculus (house mouse) ]

Gene ID: 19942, updated on 5-Mar-2024

Summary

Official Symbol
Rpl27provided by MGI
Official Full Name
ribosomal protein L27provided by MGI
Primary source
MGI:MGI:98036
See related
Ensembl:ENSMUSG00000063316 AllianceGenome:MGI:98036
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in rRNA processing. Predicted to be located in cytosolic ribosome; nucleolus; and nucleoplasm. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in lower jaw molar; lower jaw tooth; tooth; and upper jaw incisor. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 264.7), liver E14.5 (RPKM 220.0) and 28 other tissues See more
Orthologs
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Genomic context

See Rpl27 in Genome Data Viewer
Location:
11 D; 11 65.05 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (101333071..101336422)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (101442245..101445596)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene prostaglandin E synthase 3 like Neighboring gene microRNA 6929 Neighboring gene STARR-positive B cell enhancer ABC_E596 Neighboring gene RUN domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E1431 Neighboring gene STARR-positive B cell enhancer ABC_E7067 Neighboring gene STARR-seq mESC enhancer starr_30763 Neighboring gene interferon-induced protein 35 Neighboring gene vesicle amine transport 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC103134

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in rRNA processing ISO
Inferred from Sequence Orthology
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation at postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation at presynapse NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in presynapse NAS
Non-traceable Author Statement
more info
PubMed 
part_of ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in ribosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
large ribosomal subunit protein eL27
Names
60S ribosomal protein L27
NP_035419.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011289.3NP_035419.1  large ribosomal subunit protein eL27

    See identical proteins and their annotated locations for NP_035419.1

    Status: VALIDATED

    Source sequence(s)
    AK132027, BQ748836, CN831363
    Consensus CDS
    CCDS25470.1
    UniProtKB/Swiss-Prot
    P61358
    UniProtKB/TrEMBL
    Q5BLJ9
    Related
    ENSMUSP00000090305.6, ENSMUST00000077856.13
    Conserved Domains (1) summary
    cl00354
    Location:1136
    KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    101333071..101336422
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)