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DZIP1L DAZ interacting zinc finger protein 1 like [ Homo sapiens (human) ]

Gene ID: 199221, updated on 18-Aug-2020

Summary

Official Symbol
DZIP1Lprovided by HGNC
Official Full Name
DAZ interacting zinc finger protein 1 likeprovided by HGNC
Primary source
HGNC:HGNC:26551
See related
Ensembl:ENSG00000158163 MIM:617570
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PKD5; DZIP2
Expression
Ubiquitous expression in stomach (RPKM 1.1), skin (RPKM 1.0) and 24 other tissues See more
Orthologs

Genomic context

See DZIP1L in Genome Data Viewer
Location:
3q22.3
Exon count:
25
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (138061990..138115862, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (137780827..137834451, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene claudin 18 Neighboring gene uncharacterized LOC105374127 Neighboring gene uncharacterized LOC105374128 Neighboring gene keratin 8 pseudogene 36 Neighboring gene alpha-1,4-N-acetylglucosaminyltransferase Neighboring gene debranching RNA lariats 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32844

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
ciliary transition zone assembly IEA
Inferred from Electronic Annotation
more info
 
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
floor plate development IEA
Inferred from Electronic Annotation
more info
 
neural tube patterning IEA
Inferred from Electronic Annotation
more info
 
protein localization to cilium IEA
Inferred from Electronic Annotation
more info
 
regulation of protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
axoneme IEA
Inferred from Electronic Annotation
more info
 
centriole IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with centriole IDA
Inferred from Direct Assay
more info
PubMed 
ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein DZIP1L
Names
DAZ interacting protein 1-like
DAZ-interacting protein 1-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170538.1NP_001164009.1  zinc finger protein DZIP1L isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC023049, AK057406, BC033308, BQ424578
    Consensus CDS
    CCDS54645.1
    UniProtKB/Swiss-Prot
    Q8IYY4
    Related
    ENSP00000419486.1, ENST00000469243.5
    Conserved Domains (1) summary
    pfam13815
    Location:24144
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
  2. NM_173543.3NP_775814.2  zinc finger protein DZIP1L isoform 1

    See identical proteins and their annotated locations for NP_775814.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC033308, BQ424578, DR001616
    Consensus CDS
    CCDS3096.1
    UniProtKB/Swiss-Prot
    Q8IYY4
    Related
    ENSP00000332148.2, ENST00000327532.7
    Conserved Domains (1) summary
    pfam13815
    Location:24144
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    138061990..138115862 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005247198.3XP_005247255.1  zinc finger protein DZIP1L isoform X2

    Conserved Domains (1) summary
    pfam13815
    Location:52172
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
  2. XM_011512520.3XP_011510822.1  zinc finger protein DZIP1L isoform X3

    See identical proteins and their annotated locations for XP_011510822.1

    Conserved Domains (2) summary
    pfam13815
    Location:24144
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
    pfam16043
    Location:205375
    DUF4795; Domain of unknown function (DUF4795)
  3. XM_006713527.3XP_006713590.1  zinc finger protein DZIP1L isoform X3

    See identical proteins and their annotated locations for XP_006713590.1

    Conserved Domains (2) summary
    pfam13815
    Location:24144
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
    pfam16043
    Location:205375
    DUF4795; Domain of unknown function (DUF4795)
  4. XM_006713526.1XP_006713589.1  zinc finger protein DZIP1L isoform X3

    See identical proteins and their annotated locations for XP_006713589.1

    Conserved Domains (2) summary
    pfam13815
    Location:24144
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
    pfam16043
    Location:205375
    DUF4795; Domain of unknown function (DUF4795)
  5. XM_011512521.2XP_011510823.1  zinc finger protein DZIP1L isoform X3

    See identical proteins and their annotated locations for XP_011510823.1

    Conserved Domains (2) summary
    pfam13815
    Location:24144
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
    pfam16043
    Location:205375
    DUF4795; Domain of unknown function (DUF4795)
  6. XM_011512522.1XP_011510824.1  zinc finger protein DZIP1L isoform X3

    See identical proteins and their annotated locations for XP_011510824.1

    Conserved Domains (2) summary
    pfam13815
    Location:24144
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
    pfam16043
    Location:205375
    DUF4795; Domain of unknown function (DUF4795)
  7. XM_011512524.2XP_011510826.1  zinc finger protein DZIP1L isoform X4

    Conserved Domains (2) summary
    pfam13815
    Location:52172
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
    pfam16043
    Location:233396
    DUF4795; Domain of unknown function (DUF4795)
  8. XM_011512518.2XP_011510820.1  zinc finger protein DZIP1L isoform X1

    Conserved Domains (2) summary
    pfam13815
    Location:52172
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
    pfam16043
    Location:233403
    DUF4795; Domain of unknown function (DUF4795)
  9. XM_005247200.4XP_005247257.1  zinc finger protein DZIP1L isoform X6

    Conserved Domains (2) summary
    cd16269
    Location:6273
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:1190
    GBP_C; Guanylate-binding protein, C-terminal domain
  10. XM_017005841.1XP_016861330.1  zinc finger protein DZIP1L isoform X5

  11. XM_011512528.3XP_011510830.1  zinc finger protein DZIP1L isoform X7

    Conserved Domains (1) summary
    pfam13815
    Location:52172
    Dzip-like_N; Iguana/Dzip1-like DAZ-interacting protein N-terminal
  12. XM_017005842.1XP_016861331.1  zinc finger protein DZIP1L isoform X8

RNA

  1. XR_001740048.1 RNA Sequence

  2. XR_001740046.1 RNA Sequence

  3. XR_001740045.1 RNA Sequence

  4. XR_001740047.1 RNA Sequence

  5. XR_924113.2 RNA Sequence

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